oD wet ow + GF... pe .te coauiitvens a realetir stat wtere: ==~-eeeew ~~Mt te meade. However. the jprabieam sreadven: » th eotimation of daw rereived by fhe rdesnbael eee reaped ~ a Steck the fatal dour reverved) he we War tecte war cab-uinted were menrured fee a ne cc 2 rine 3 for whove the groniwi «ar. ft » prab few Re rar of the planer genmetry of 1poeere ont thr energy of the for thn and the position of the individual during es- of the hndy wouki he greater than for the same preeret real proctical difiruitws. ebie the! dove eatimetes will br available from dommetry devices or from dene contour irae posere. Mome of the diffcultws of reiying heavily on cone estimates are nhvinua, The es- act position of the individual and the degree of shielding will not be known precisely. The daemmetry device records the done or a done rate which may not reflect accurately because of shiekling, energy dependence of the device,etc., the deposition of energy within the individuals at the ate of interest, namely bone marrow and gastrointestinal. tract. More important, because of individual differences in senutivity, individuals expored to the same measured done may differ widely in their responses. Thus, estimates of dove calculated from cose rates oF derived from an integrating dosimeter or from position of an individual during exposure can- not be accepted as the best index of the probable fate of an individual, or ax the final index to therapy, triage or prognosix, Since the syn- dromes of radiation injury have varying svmp- toms and are done dependent, the symptomology is in sense, a personal indicator of one's fate. Experience with human radiation injury at Hiroshima, Nagasaki, with reactor and critical assembly accidents and the fallout ac intent described herein strongly suggest that the hest method for estimating the seriousness of exposure at the individual level is the symptoTratic approach, As with any disease, an accurate appratsal of the patient's condition results only from a thoreugh evaluation of the history, physical and laboratory examination (see Section 6.525 below). 642 lIafweace of Geometry of Exposure on the Effective Dose, LDQ. for Man The riftnence of the geometry of expusure on nererere( sue iate, the deve rate at the center chump rate from a hegh energy Xray swurce, measured in arr at the protimal skin surface. The effects of fallout gamma rediation would this he expected to he greater, for the same done measured in air, than would laboratory redistions, The high initial incidence of nausea, vomiting and diarrhea in the high-expnsuore Marshallese group, and the profound neutrophile and piete- let count depression indicated a greater effect than might have heen expected from 175 r im the laboratory, in keeping with the shove. As indicated in Chapter [V, from this value for the dase received, and from the degree of leuko- cyte depresion it is posible to estimate the done at which a small incidence of mortality would have resulted without treatment. These con- siderations woukl place the threshold for moetality at approximately 225 r, and the LD, at approximately :‘Mal rc for fallout gamma redistion, ft is also clear from the above consider- ations, that a figure for an LD, for man, independent of the condition of exposure is ementially menningtess. The LI. figure of 3506 is below the value of 4) of 450 r commonly quoted (7). A recent re-evaluation of the Japanese Nagasaki and Hiresbhimea bombing data has resulted in a tigure well above the 400 or 450 7 value for the immediate radiation fromthe bomb. The error in this figure. as well as that obtaine.t Fry the Marshalle-e data, is very great. Hovercr. the profound hematological effects seen in’ the Marshallex: would argue strongly for lowering. ov at Jeast nod raising, the current LDA ei. tuates far cil defense amd other planning, this particularly umder circumstances where falleast the effective deme is disctissed in Chapter f, and tedsations may Ulse seesmererse) leebal bee fcr tnaiin Chapter DY. ‘ . Shad bere agg on mi be expected te be the chef 1 Maoh.

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