-2in Baltimore. He emphasized that a study on the aging process in sub-human primates has. been badly needed for a number of years, but the magnitude of the undertaking has prevented anyone from undertaking it so far. The question was raised as to the desirability of getting more background information on other animals before going to monkeys. The group was unanimous in feeling that more information from lower animals would not help substantially in this study. The only other larger animal considered was the dog, and it was pointed out that the experiment would be just as costly, in time and money, as the experiment on the monkey, and would not take the place of the monkey experiment. It was thus the unanimous and emphatic consensus of the meeting that, with the wide-spread use of radiation today, and its possible use in warfare, no time should be lost in initiating a study in monkeys. (2) The magnitude of the project: There were various estimates of the desirable number of monkeys to be used, ranging from 200 to 1000. A reasonable goal appeared to be about 600, although it would not be necessary to start with this many. The consensus was in favor of using the Macacus, imported from India, prepubertal, and the age estimated from the teeth. Some in-utero irradiation experiments should be done. The figure of 600° monkeys should give enough for several dosage levels, with enough in each group so that experiments of different sorts can be done on sub-groups, and with adequate controls for all of them. (3) The location of the project: It was the consensus that climate should not be considered as a factor in selecting the location of the project. The Macacus is not a tropical animal and if given adequate space will thrive in climates such as that of Wisconsin. nd There was considerable sentiment against establishing such a project at a university because of the magnitude of the project and its long term nature. This is more in the nature of programmatic research, and universities are not as suitable for this sort of research as a Government laboratory such as the National Institutes of Health or one of the Atomic Energy Commission laboratories. There was strong sentiment against putting it at a small laboratory like Orange Park, since there should be a large active scientific group there all the time, not only those working directly on the primate problem, but it should be part of a scientific community, with a good library, etc. This project will require . a good deal of space, and an estimate of 30 acres of land, as a minimum, | has been made. DOS ARCHIVES