in the medium. Analysis of the cell potassium, and study of the pdbassium- hydrogen exchange across the surface 2 have shown also thatthe sti layers of the cell. This Stimulation does not ‘depend on any chang@ ' internal potassium level or the rate of its exchange, but only’ on external ; potassium-ion and hydro gen-ion. concentrations - The most a number of the subsequent steps in the carbohydrate metabolic sys Application of these processes will be extended to the study of phenomena to other micro-organisms, and to the organs of higher as the diaphragm and the intestine. Mechanisms of Virus Infection. (UNCLASSIFIED) in the. Looe ular The mechanis virus infection are being investigated by a research group at the sity of Colorado. The virus under study is the bacteriophage whi destroys the common colon bacillus. Although the bacteriophage i rather specialized type of virus whose behavior is not necessaril characteristic of all viruses, it is unusually convenient for 1 study, since the infective processes can readily be followed in tube mixtures of the virus and the host bacteria. In such mixtures, the virus rapidly penetrates the bacteria and reproduces itself at the expense of the host cell materials. bacterial cell finally ruptures and releases large numbers of badteriophage to infect other bacteria, and this process continues as lo the bacteria supply lasts. The results of these experiments usi radiation as a tool to alter the virus and its physiological efffcts have been making considerable contributions to the understandi basic physical mechanism of this infective process, as regards attachment of the virus to the bacterial surface; (2) the loc down of the surface and penetration of the virus into the inter’ and (3) the basis for the different specific immmities ofthe ¢ strains of bacteria to the several strains of bacteriophage. Radiation Effects in Animals. (UNCLASSIFIED) Experiments at Oak al Ridge National Laboratory are in progress to determine the biolpgic and pigg, effects of neutrons as compared with X rays in mice, guinea rats. Cyclotron-produced neutrons and 250 KVP X rays were use ARCHIVES