AC eh E34} THE WORCESTER FOUNDATION FOR EXPERIMENTAL BIOLOGY Shrewsbury Massachuselly April 2, 1954 Dr. John C, Bugher, Director Division of Biology & Medicine Atomic Energy Commission Washington 25, D. C. Dear Dr. Bugher: I would like to take the liberty to ask your help with the following problem, We have, during the last years, workedijn this Institute on the study of the biological synthesis of cholesterol with the help of radioactive carbon, [In the course of these investigations it has become quite important to procure comparatively large amounts of cl4 squalene. While we are able to make comparatively small amounts of this substance without great difficulties, larger amounts are not easily available. It came into my mind, therefore, whether the A.E.C. may not have-the possibility to give us livers from sharks caught after the tests in the Pacific, provided that the radioactivity in these organs is at least to a part due to cl being incorporated, Any help which you could give us with this problem would be greatly appreciated, Yours very sincerely, Erwin Schwenk, Sc.D. ES/pg ORY HUDSON HOA LAND, Ph. 0., Se. D. GREGORY PINCUS, Sc. D. Executive Director Oirector of Laboratories RALPH | DORFMAN, Ph. 0. associate Director of Laborators ye # RRUCE (RAWFORD DO ARCHIVES|