10 Dental Survéy— “ [ntra-oral examinations were conducted as past-ai the phvsical examination. All patients were examined with mouth mirror and explorer. Illumination was by standard operating Table! Age Distribution in Rongelap Adult Population, 1959 Used in Aging Study light. Salivary BH was taken by use of pHydrion on all subjects who were not eating candyor any Exposed = Unex posed Age. vt Mo F M F Dental examinations were carried out on the following groups: 30 children at Majuro; all the adults and children at Rongelap who were in the phvsical examination group: and a number of 20-24 25-29 30-34 35-29 40-44 45-49 0 2 3 l ¢ I 5 1 2 4 2 0 ! 12 3 + 5 2 5 ° 3 + 3 3 L2 21 .3 {3 13 5 I 0 3 3 I! Studies of Aging Criteria 33-59 50-64 65-69 0 3 other foodstuff. Saliva samples were collected from these patients at the time fH determinations were made. Intra-oral radiograms were not available. children at Utink. Although the expesed group has shown no outward evidence visible by gross observationofany accelerated agine effect of radiation, it was thought desirable to have available measurable criterta of possible age changes for use during normal physical examinauon. Therefore the over-all objective of this study was to establish tests to evaluate anv possible radiation-induced senescence in the exposed group compared with the un- exposed population living on the same island. However, the data (presented in a later section on results) collected during the 1959 survey (5 years after exposure) showed no apparent differences between the exposed and unexposed groups. Therefore the data from the two groups have been pooled with the objectives of presenting the methodology, indicating the trend of changes with age of the various aging criteria chosen, and attempung to determinea biological age score for individuals and different age groups. This study was hampered by the small number of people involved andthe lack ofvital statistics on the Marshallese people. Another difficulty has been the uncertainty of exact ages in some cases, particularly in older people. Data on aging criteria were recorded only on adults 20 years of age and over. Of the 126 adults, 42 were in the originally exposed group and 84 in the larger comparison population. Table { shows the age and sex distribution. The ages were reasonably well distributed except for a smaller number _of older people (>60 years of age). The age criteria chosen were based on changes generally believed to be associated with physiological senescence and represent only a small number of the possible ones. Theywere selected witha 1185960 30-34 2 0 0 I 6 0 3 3 2 0 1 Qa0 70-74 ep >80 2 73-79 2 1 Q 2 l 3 3 0 Total ? [4 5 5 126 view toward ease of assessment during routine physical examination under feld conditions, time limitations, and language barrier. Therefore, un-” fortunately, tests of vigor and functional capacity were necessarily limited.* Of the 15 criteria selected, 9 were measured directly and 6 were estimated on a 0 through 4+ scale. Five tests involved the integument: (1) skin looseness, (2) skin elasticity (retraction time}, (3) senile changesin the skin, (4) greying of the hair, and (3) baldness. Four tests involved the speciai sense organs: (1) accommodation, (2) visual acuity, (3) arcus senilis, and (4) hearing. The cardiovascular system was tested by (1) systolic and (2) diastolic blood pressure recordings, (3) peripheral! arteriosclerosis, and (4) retinal arteriosclerosis. There was one test of neuromuscular function. Vigor was measured by hand strength measure- ments. The test methods are described below. integument. A special skin caliper was designed for measuring skin looseness and elasticity (Figure 8). The legs of the caliper can be opened to any desired degree up to 5cmon scale 4 byad- justing screw B. The spring tension when thecaliper is closed on a fold of skin results in a pressure of about 500 g. The inner and outer surfaces of the legs are calibrated in millimeter markings (C). *Several tests, such as pulse and blood pressure response to 4 two-step test and vital capacity, were tried but not used because they proved unsatisfactory.

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