42604
UNIVERSITY OF CALIFORNIA
DONNER LABORATORY AND DONNER PAVILION
BERKELEY 4, CALIFORNIA
May 2 1963
Dear Dr.Meyer,
I received the pipet, the serum samples and
the data on your subjects. I have distilled the serum, and
when our new scintillation counter is set up I willthe
water samples and send you the results.
samples monitered in Donner Eab's
+ had all the water
whole body cgyunter just
to make sure they were not contaminated with Cr¢
As far as I can determine,Will hasrt done
any work on the relationship between blood volume and lean
body mass in the four years that I have worked for him.
Nor can I find anything published by anyone at Donner Lab
on this subject.
The most recent article that I know of is by
F.P.Muldowney of Harvard Med. School in"Techniques for
measuring body composition" p 212. 1 enclose the title , page
of this publication so you can look it up. Muldowney géves
the linear regression of red cell mass(y "on lean body mass
(x) as
y= 32.74x
+
155.17
Is this the formula that you are looking for?
Dr. Howard Parker the Associate Research
Physician at Donner said that about 8 years ago, Will and
others tried expressing blood volume in terms of o¢/em of
lean body wt. rather than cc/ gm of total body wt.Theoretic
-ally this shouldhave produced a better correlation, but
after trying. a couple of hundred patients this way, the
researchers decided to go back to the old method.fhe Clinic
still uses the old method.
I will send you the water volumes, the Kgs o
of fat and the lean body mass on your subjects as soon as
possible.I will also send you my calculations for your file.
We were not able to establish radio contact
as we had hoped, so we have no news that is-net in the newspaper.
The mail
service has also been very poor and we have
had only one letter from Will.All he said was that some of
the scientific equipment has broken down and this is spolling some of the planned research.
Sincerely
i
)
Rosemary Hughes
P.S.
Please forgive the typing..I'm no _typist,
and pecker.
f
just a hunt