te ee ee
23
MEDIAN WEIGHTS 1958-963
-
T_T
17
aors
1
|
+t
71
FT
20)
40- a EXPOSED
~~
m= ~o CONTROL
“|
CHILDREN OF EXPOSED
PARENTS
me
_
5
6
t AGE (YRS!
b
\
a
“ae
*
:
b CHILDREN OF UNEXPOSED —
PARENTS
;
20r{
ous
4
?
6
a
8
dd
0
12
AGE (YEARS)
a
ié
16
Figure 16.
e 3.
thought to be malignant. Sections of the tissues
were reviewed by a number of pathologists, all
of whom agreed that the nodules were not malig-
nant and resembied in many respects adenomatoid
goiters seen with iodine deficiency, with its characteristic regenerative rather than neoplastic proliferation. However. in the Marshall Islands, where
fish and sea food are mainstays of the diet, iodine
deficiencyis not likely and goiters are rare. Figure
10 shows a picture of the gross appearance of the
nodules and Figure 11 shows a microphotograph
of one of the glands. The likelihood of these nodules being radiauion induced is discussed in the
Summarizing Discussion. The two girls who had
complete thyroidectomies developed signs of hypoparathyroidism which responded to treatment.
STATURES (938-1963
CRN 4SFTER Fac.ouT
“RILOREN OF EXPOSED
“ARENTS
[HILDREN OF UNEXPOSED
RENTS
a
~
ee
3
6
?
AL AGE (YRS)
gure 15.
TT
o—— £ xPOsEo
GIA S
TT
o@ —-© CONTROL
-_
—
Parathyroid function returned in No. 17, but No.
21 sull requires therapy including thyroid extract.
In the third case (No. 69) oniy a partial thyroidectomy was done, and she requires no therapy.
Note: During the | !th-year survey now in pro-
gress (March 1965) 3 new cases of thyroid nodules
in the exposed group have been detected. Two
*Secuons of nasuc were newewed and reported on by Drs. S.
Warren, New Engiand Deaconess Hospual: GH. Klink, Armed
Forces Insotute of Pathotogy. C J. Saahl, U.S. Naval Hospatal a
Guam. H 4. Jotnson, Brookhaven Navionai La'-oratory, and
8. Landsav, Univernry of Califorma Medical School.
‘iabeoed eee
WEIGHT | POUNDS)
SS
NX
8 8
TOT TT
a
Ld
STATURES 1958-18630
MEDIAN WEIGHTS (958-1963
TOT
/ge
8
WEIGHT (POUNDS)
1204
BORN AFTER FALLOUT
eT
AGE (YE aa$)
Figure 17.
were in boys 12 and [7 years of age and one in an
adult woman 41 years of age. The nodules appeared grossly similar to those described in the
teen-age girls in this report, and these cases will
receive study and treatment.
Greuth end Development Studies. Analysis of
the statural data from the 1963 survey indicated
the persistence of the trends previously reported.
As shown in Figures 12 and 13, no difference was
apparent in median statures between the exposed
and control groups amonggirls and between giris
born to exposed and girls born to nonexposed
parents.* Among the boys, however, retardation
in statural growth of the exposed group between
the ages of 5 and 12 years as compared with that
of the control group was again noted (Figure 14).
The difference in median statures between boys
born to exposed parents and those with nonexposed parents was also evident in 1963 (Fig-
ure 15). This difference has been attnbuted to the
fact that the boys in the group with exposed paren
were, on the average, 4 months younger than the
bovs in the group with nonexposed parents.
Nostatistically significant differences were noted
in body weight curves between exposed and con-
trol children ¢ Figures 16 and 17}, In skeletal maturation, the trends reported in the previous studies
*Dr. K.M. Gnéith of the M.D. Anderson Hospetal did the
sausucal analyers.