the different types of circulating blood cslis, esturl
imentel observation confirmed thats

(3)
(b)
(c)

3,

expere

The short-lived white biood-cells: disappeared -or

were reduced first, the lymphocytes in less than
24 hours, the yranviocytes within 72 hours.

Thé blood platelets (intérucdiets life span) were

reduced next--first reductions in rats ¢t about

five days.

The red blocd cells (Long-lived) were the last to

show reductions.
In the rat, repeneration wes evident by the fifteenth to elghtcenth day in most cell *ypes except for the. sranvlocytes was

still. incomplete by the twenty-fifth day after exposute.e In

other species, repeneralio:. may ba slower, The lymphocytes
were st&il more crazily reduced after twenty five days than
were the other cell types.

ke

In aninzls receiving large doses of radiaxftn, a’ sharp drop in

numbers of red blood cells cccurs around the seventh day after

radgfition.

This is thought

be due to bleeding, nutritional,

factors, and possibly to othcr ]jtile-=understeod factors and
not entirely to simple destruction to partnt cells. This sudden
anemia dces not occur with lever radiotion dosages,
5S,

In certain speciss (cnd perheos
Gamage is cccompanicd ky ther

severe radiagfton
sincagulant heparine

7
like substunee dute the circuln:

which, tesether with the reducui

in en sbnoral tendeney to ase
re

bleec

body as e Whole

I

haf

Q

t

Oe ee 8 ne

SUmuerise but very important

tee

Ge

oi

5

na

bo

G

5)
C3

ry

pe
re
fle
ta

POE OT
AF A

i

whlatolcts, results

-

Repeated Gmali,necceeer
Doses
t2 the
enareren>

The experimenta

ad clots shovwly

etd

since if is coronie radiation reveatercly received in onall deses which is the commonest

So.m of raciation exposure in man.

Ip is clear, horcver, the. within limits3 the effect
i

.

chronic radiation definitely incrcaces the incidence of leukemin ts enters.

&

4

i)

m

Q
Q
ta

3
oo

a?

8

e

eo)

ton

ao
a
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i

o

{f

ee

aa
pele
fe

{-te

3Qa

[ote

is of great importance regardless of how sm

ct
=
Q

Ny

of chronic redietion is cumulative and thyatthe tote) docage rectived by an organisn

Mirely,

after upparent recovery from chronic radiation, injery te the blcod-fermins tissues
and sevcrei. edDnormelities uuy develop even after raciation has vcen Giscontinued,
Radiation to a Local. area of the Body
It has been the subject of much controversy thether or not local sadiatio:
mAY, in some direct way, damage hemopoietic tissue cutside the Bield of radiaifon.

Local

Select target paragraph3