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Méfgn<—
auG 12 1988
{
PECHNIQUES AND STUDIES IN THE USE OF IODINE 131
Dr, aobert Fink, Research Blochemist, Birminge
hem VoAe Hospital and Associate Clinical Pro=fessor of Physiclogical Chemistry, School of
Medicine, University of California at Los Angele:
(Abstract of a lect
eture celivere@? in s University Extension Course at
U.C.L.A. on “The Application of Nuclear Physics to the Biological and Mede=
{eal Sciences")
The metaboliem of iocine has
research duri
subject of a large amount of
two Gecades since the thyroid gland wag shown to cone
very marxel degree as ccnopared with cther tissues.
racioactive iodine became
sgo and mace it possible
under noriral cone
acel rannins
toe Le Learmsd abtut
the blicod etresm
Ens
baés ts
mwas
nots the thyrcie ecptures Lodine from
and converts it into
Cong
Pi
tha thyrai@ bernone
whieh controls
Ge 2
Same recently devciored chromatovrdphic tschmicvgs show promise of
being the tocis reculped for
the {ob cv Pillins in mush of the miesing
information esout this process and perhaps many others eas woll.
For ex-
tracer tecinmiques have hsen used in conjunction with
filter paver shromntography, a vracedure in which a tiny greplet of body
pe
flui ¢@ or tissue extract placed
tS
inci vicusi
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—
chemical
on a sheet of filter paner is split into
«Ymponents> by a ifcquit wrien creeps down the paper
and carries the echsmical substances prasent in the cririnal droplet along
at different rates.
then eiven a chromate
Spraying the paper with « suitcble cclor reagent
m showing colsrec spots eccrrespending to the posi-
tion texon by the shemical substances present in the droplet in relatively
high concentration.
If radioactive substances are
present, nowever, pre=