wa Te aed eoaStesswee seat Code Breaker Beckman’s exclusive Tm Analyzer: the only lab-proved system specifically designed to determine helix-coil transition temperatures in nucleic acid preparations (plus a broad range of related biomedical/research applications). /’s ready-made for deciphering the genetic message. Together with a Beckman DB®, DB-G or DK Ultraviolet Spectrophotometer, the Tm Analyzer performs high and wide in the 0-200° C range: High pro- gram: ‘inearity. Wide temperature range. Highly accurate temperature readout. Wide range of program rates. Highly stable temperature control for isothermal studies. And it provides you direct x-y recorder capability. Analysts can evaluate the Tm curves obtained for information on: # Native state of DNA or RNA preparations * Relative purity and homogeneity of various preparations = Relative 8 DECEMBER 1967 proportions of guanine and cytosine residues in molecules # Effects of irradiation, halogenation, or other induced physicochemical changes #® Influence of pH andionic strength on helical sta_. bility = Degree and reversibility of thermalt denaturation = Length and compositional homogeneity of the helix » Properties of various homepolymers of constituent nucleotides = Mechanism of nucleic acid chain replication. For full details on this unique Tm analysis system, contact your local Beckman Sales Representative or write for Data File #800F. The people out front in background and back-up... Beckman: INSTRUMENTS, INC. SCIENTIFIC INSTRUMENTSDIVISION FULLERTON, CALIFORNIA * 92634 INTERNATIONAL SUBSIDIARIES: GENEVA; MUNICH; GLENROTHES, SCOTLAND; TOKYO; PARIS; CAPETOWN; LONDON; MEXICO CITY 1255