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105
tay
Aside from the two subjects with bran k
hypothyroidism, there bas been an
an other cases Phe evi dence
puthryrontions
fry
possible
af
suspicion
Increasing
two boys who
supporting this concdusiun Is suntmanzed in Table Ho Fhe
dose of 1150 rads.
developed inyxocdema had received an estimated Giyroi
population, who had approp! tale testing
In addition al least tive of the RK ongelap
oF decieased thyroid reserve [7/4 tu
isin
before surgery, had either hy pothyroi
ctomy bave shown tlevaliun
addition a nuaiber of subjects with sub-total thysorde
ii, when them thyroid
sc1un
if
reduction
and
ions
convent
TSE
nserum
to. [his 15 signtiicant since in
leplacement scliedule Was not mporousdy adhered
y i nod associated with Giatik
general subtotal, Uhytoimectamy or lobectom
aiten hypetliophy to
hypolhyruiisma, since Hie remaining Uhyrodobe ay
tidividual. Ad} the
the
of
nts
equircime
6
hormene
supply the needed thyroid
uf a young age, aid
subjects su tested and fisted in Fuble HP were irradiated
1150 rads Hecatise of the
therelure receaved thyroidal dusage of about KOU
yeven lower cal ulated
als
midividtu
A
otdisi
laypolbiys
pussible
vl
suspicion
unvperated exposed
duses, a series Of studies of thyroid aeacive in previously
te port summarizes the data
Marshallese was itiited am 1974, aad the tollowing
obtained tn (his study up to the prescat tine
times the duse from
Hater One ol these,
thyrand lestons Four Rongelup chidicn were exposed
time the thysou was functional),
a boy expused a p22) M4 weeks gestativn (at which
age 20 A anuch simalies proportion
had Denn nodules of the thyroid removed at
lities. Vhe
of the Uguik group of either age hus developed thyroul abnorma
population (compared
occurence ofthree thytout cancers in the exposes 1 Utink
padialion exposure iy Mie
with fous tthe Rongelup group) appeals ty maplicate
thai would be
actiulogy, but the high tacidence bs puzéling sue iis grealer
Urere does not appear to be
predicted busee Jon Rongelap and Japanese data, and
group compared wellt Che moc
any incaease In benign Uiyrond Gimouss in thal
pieater prevalence ma the Kongelap group.
subgecds sia
‘The high meidence of Unyrotd nodulaidly in the irradiated
subscquent
with
gland
the
ol
adislton
tr
dking
dala
agiceal rent wilt previous
Since ''1 is considered auch
development of thyron! nodules of & arco [Of
Ibis Falher sucprising that,
less Cumotpena for Uiytoid tumours than X-aays,
thyroid dose we the
the
to
nes
gudsorudi
of
ion
Contibut
in view of the iarge
thal noted following
Marshallese, the sisk factor (ish /rad) 1s compasable wal
shourtX-ray exposure. This may be related (o the presence of nore potent
d fur two to three
accuumte
which
albout
|
i
present
jodine
of
lived isatupes
d
exposed over thie ape of ten have develope
Gine cl exposure, and Over 156. of Hhuse
.
nodularilies and
have been resected surgically bhe incidence of thyrond
tu lal gut are depicted
exposed
groups
age
various
the
in
duses
estimated thyroid
of those individuals in thie
wn Table bo Hts appatent that more than two-Uinds
(he age of ten al the
combined Rongelap and Aalmgnae groups, whu wele under
IAL A SM-224/607