Plate 21. (X100, H&E) Epiderars: Extensive transepidermal damage (with slightly less involved zones on erther side). Loose lamination of stratum corneum, absence of stratum eranulosum. Parakeratinization with exfoliation of pigment containing cells. Disorganization of the malpiynian layer. Dermis: Mald edema of pars papillaris with indistinct capillary loops. Perivascular cellular infiltrate (lymphocytes and mononuclear phagocytes), in superficial corium with telangi- mw™,.. ectasis. Plate 22. (X¥100, H&E) Epidermis: Arcades of minimal damage occur in relation to excretory ducts of sweat good width glands. Stratum granulosum of and shows scant alteration. Underlying stratum malpighii shows decrease in pigment. In the deeper portion of the overlying, loosely laminated stratum corneum moderate amounts of pigment, however, are present. One narrow arcade of more severe transepidermal damage at the left of the photomicrograph shows alteration of the stratum granulosum with intercellular edema, pyknosis, swollen nuclei, and pigment scattered throughout. The latter is especially dense in the contiguous parakeratotic material. Dermis: A moderate cellular infiltrate, chiefly perivascular,is most pronounced in the Old superficial pars reticularis where there 1s a mild telangiectasis. Case 24. Case