[| USDOEA j , Pa document consists ef OMM™. t FL of “ae -" er, i. D., Director SAE? Biology and Mecticine i pages September 16, 1954 ey, Biophysics Branch Biology and Medicine “~ COMPUTATION OF I-131 DOSE IN HUMAN THYROIDS RESULTING FROM CASTLE FALLOUT IN U.3. SBP: RAD BEST COPY AVAILABLE Dr. Dunning has asked me to computa for you from the svailable data the I-131 dose in human thyroids resulting from CASTLE fallout in the U. S I estimate the total dose to have been less than 1,5 rep, as compared with the sible dose per year of 15 reps (0.3 r + maximum permis- S| wi). The basis of the caleulation was as follows: Observations on: thyroid Activities 1. LeRoy measured | human thyroids. fron Chicago antopsies by scintillation counting, ranged from 0.5-1.6 x of July 12, 195h, activities /em. dudging from half-life, the activity was quite tealy I~131. hr. Dunham believes the Jocal hospital I-131 contaminationaight possibly be the source, rather than fallout. 2. Harley measured 1 human thyroid from NW, Y. after digestion and dhemical separation of I. This. technique gave high sensitivity but Harley is not positive of 100% recovery. So I-131 was demonstrated, and an upper limit of activity was estimated at about 2% that observedby LeRoy. 3+ Looney and Colodzin at MMRI measured several human thyroids from Washington by scintillation connting. ‘Their results _ a valne. . kh, Hardin Jones has observed I-13] in the urine of some patients in San Francisco, sone in other patients, His figures are not yet available to me. | opt gouupu Aub ce were negative, with an upper limit of about 5 LeRoy! s [ORNL ED 2; “oy #&= 6 Cantos, Series 4 - f RG _ toe thle, Collection + ~ eé 5. Yan Middlesworth, Hardin Jones, and others measured the activity of cattle, sheep, hog, and dog thyroiiis in June. o On cattle and sheep their resulta (extrapolated to July 12, a Middlesworth found hogs and dogs to contain much less i LeRoy's data) were approximately the same as IeHoy's, Van OFFICE p> _puppfounddogs "approximately as nigh ie aw - DUDLEY: MMack SURNAME & |...91.6/5), DATE ® {. - 0 - ™ AEC-318 (Rev. 9-53) MIAAP. DANI/ a = all a UG, 5. GOVERNMENT PRINTING OFFICE 16—62761-3 MANAG . ENENT - Af “oe BOE ARCHIVES =