106
LARSENetal.
TABLE Ii. PRIOR EVIDENCE OF THYROID HYPOFUNCTION AND
CALCULATED THYROID EXPOSURE
Description
Subject
identification
Thyroid
estimated dose
number
(rads)
1. Two subjects with frank hypothyroidism
~ 10 years after exposure
3
5
2. Five subjects with hypothyroidism or
decreased thyroid reserve pre-operatively
2
20
810-1150
810-1150
3, Three subjects with impaired thyroid
function following subtotal thyroidectomy
1150
1150
33
810-1150
42
810-1150
65
810-1150
17
810-1150
21
810-1150
69
810-1150
TABLE III. RESULTS OF TSH STIMULATIONTESTS IN EXPOSED
RONGELAP SUBJECTS AND CONTROLS
Mean + SD
Mean serum Ty
prior to TSH (10 U 1M)
(ug/dl)
Mean serum Ty,
increment 24 h after TSH
(ug/dl)
Controls
6.0 £ 1.7
4.2+1.3
Exposed Rongelapese
(n = 26)
6.6 + 1.7
2.441.2
METHODS
Studies were performed during the annual or semi-annual visits of the
Brookhaven medical team to the Marshall Islands. Subjects were instructed to
discontinue thyroid medication for two months before the studies of thyroid