peared to show a
cb
oT IN EATING
ee oneastent pautern toa
did the leukoe fe ce in ~
Platelet Cou ont
one individtial, consboerea isa ta pread vesporiss
Ima non fatal Papeur ese
inelicated stunt
parent low app oxi ites co iibiy jt Vhs nu
trend agrees wth
dot
een the Marshiuese
and Americans exposed to tallout radiation
It is worthy of nore
|. ue the pesrod of peas
incidence of purpur
oie tie .fapanese viet m-
occurred between he vor
ond Joth dacs wtae
corresponds fo the top
of masimium priatedler
depression in thee yposed Viurslrillese
4.43)
Although vitae
os
|
Viamios ©
Ne
cna
Ma
Soe type of or wetter
esunma and net tron
iit on was rece ved
ibid
opoperiscn maw be cf vate
ut
Some findings tn the petmmtologel resporseare pointed off
0
foun form e urls rise
white and neutrorare counts over the ips fess
days, similar te that ee rearhy i tie Vmereius
group Was observed irtformily © be ott oree
high-expostre tat
oor cetanb cases. the cota
white and leukooste o bute continned te
a8
some degree oft depress)
ata tae 7th
wee
cv the ostier ste eount. ip ina
Uals exposed ta te
the p
Initial marked epee ss or
t
a
a0 rer. stiawee 3
[nomiost
ines tea
lymphocyte counts
ema ned ut fas
vives
throughout the peries cf abservation sb peat
let counts were date
times of
™
ae
he
to
THEN TE tes
ierefore
pp
HAE VLPs gs ett
FNO COUNTS ware
cot
Pes-lon
ae iad,
wa
comp erstbe
tose)
‘were
irvivor
eat
lo haves obraied
ay
o ths
fp cea close dons besor
however, the { bateeles
the first 72 hea
Werent
res) oh
sistent wath the eon og
present -tudies
tot
abt
Hots dba
Peep
Poeoreips
perebec
oo
4
bak
boata
bt
week.
wath week.
Recovery
was
not
complete
by
The lyvmphocvre depression was
abil and tuurked. recovery was not evident by
he feta week. Minimum values for the plateereomits vere obtuned between the 25th and
WEP ESN
with Animal Date.
The time
ina severity of peripheral blood count
lange followmne total body radiation in ante
and the vondit one oe sie aire vere roarked
different from either Oe hapaese or the €rroiuys
T situations, 2 npee ooniponent of penetrat ne
However. of
i tota count, with low values continuing into
he Tth
remds
gonne aceidents
absolute count
ohihe leukocytosis was followed by fluctuations
Ath)
Accidents
bevond.
Toe Argonne Laboratory aecident (19) inceived four cndividuals who were estimated to
wee recerved 116, 127, 60 and 8 rep, respecoe The tindings ithe two hiehest exposed
boljoddbels tn venerar were consistent with
Hosea the present study. An initial neutro-
stole
Comparison W-th Data From Laborarorm
thus attempt~
RADIATION
Cras
thats tics been exam.ned critically recently (15),
mat othe tollowing eveneral conelusions ure
rresenred,
a
Ano oipitial rise ni total white count (re-
Hected an tae nentrophile count) may oceur.
Phereafter the magnitude of depression of the
roral white id neutrophile counts, and within
Tnats here duration are a funetion of radiaMon dese,
\ secondary or abortive rise in the
tera} white count cretlected in the neutrophile
lymphocyte count) tay occur, followed by a
econd decrease, There is little -pecies cditferrave tn the rate of depression of the total white
hr pentropraile count at comparable doses: howrver the rite of recovery and time for complete
eroversy i: quite different my various species.
siiill umatials (mouse, rat, dinmster) show relavely complete recovery to control levels, even
vodiases in the lethal range, by the end of the
mh week oor earlier.
piate
Datn on dogs are inade-
a tadieate when recovery is complete:
lowever, retin to control levels at high dose
evels cas cot aecnrred by the oth week. swine
quire ota ES or more weeks for complete
BrEveT A
ba The response of Lymnphoeyvtes is essentially
dentieal acl animal species, Depression can
oe deteetes withitn a few hours, and recovery
ren tied pina valnes cachieved in 36 to 48
ons) reciires Jonger than does neutrophile
Pe AN
Ainpboestes fall to very low levels
&
LPERU TS