09-21-1994 12:13 5162825311 BNL-MED. DEPT. P. 006 +1- will not be known precisely. The dosimetry device, records the doge or done rate, which may not reflect accurately, because of shielding and energy dependence of the device, the deposition of radiant energy at the site of interest, ely the bone marrov and the lining of the intestinal tract. The problems associated with predicting medical effects from pHysical’ estination of dose can be further illustrated as follows: it 1s apparent [that done estimntes available will be air doses. The dose received by the aint is of academic interast only, since the degree of effect in living things is due tol the deposition of energy and its distribution in the critical tissues. Accordingly| one must know the depth dose nattern or sore precisely the pattern of absorbed Joss in sensitive critical tissnes. freat length This problem has been explered experimentally at and is deseribed in detail in references (17). More need not te said here other than the fact that the uniform fleld cf radiation coming at an indiviflual fron all directions is sore effective per r in air than dose of radiation quality. pf directional In urban areas there may he shielding from the fallout fielf or inhomogeneities in the field due to drift in dry windy areas. With by buildings the prompt radiation shielding may te significant and the proximity of large buildings may ser~ Jously influence scatter ani perturb the uniformity of the radiation.]| Lastly a fallout field may be made unidirectional by heavy shielding from buildinge on one side, Thus estimntas of dose calculated from dose rates or derived frbm an inte- frating type of dosimeter that adds up to the total dose received, or Form position of an individual during exposure, cannot be accepted as the best indexfof the pro~ -bable fate of this individual, or as the final guide to treatment. interested in the individual from the The stardpoint of sorting casualticp physicien is with some chance of survival ard those for whom nothing can be dene, and of squa importance the troop commander is interested in the froupa of over all prognosis of large individuals in order to make plans for disposition and replacement. ese two different desires cannot be completely met by physical estimates of doge. ever, nature has been helpful. The manifestations of radiation injury How Wary vith

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