09-21-1994 12:22
5162825311
P.024
BNL-MED. DEPT.
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-22evident that the life srortening is some function of the dose of rad} ation,
extrapolation from mice toman is extremely difficulty.
Hovever, the
Tt is unli kely that any good
statistical analysis can be msde on the Marshallese because of the
1 nunbers of
imiividuals and the uncertainty of the precise birthdate in the old e
groups.
There
has been ons death in tho Roengclap group who at autopsy showed ovid ence of heart dis-
ease.
In the larger group from Utirik there have been five deaths.
The number of
deaths is comparable in both croups one havinz received 175 r am t t > latter only
i4 re.
To date one must conclude that there lus been no significant evidence for
prenature ageing or shortening of the life span of the Marshallase,
Leuxemia end Cancer
Loukemia i5 one of the things thst is know to have occurred in the Japanese
ama is prevalent in ixradiated laboratory animals.
To date no leuk fs has occurred
and there is no evidence of leukumfe tendencies, This is being stud ed intensively
by the uso of alkaline phospnatuse stuifes on the granulocytes ani rasophile counts
on the blood,
It lias been shown by the stulies of Moloney et il.,
In Janan that a
basonhilisa and Qacrease in alkuling pho subatane precedes the cdevele pment of Jeuxusia.
Genetic Rtfects
The small number of individuals involved and the tnadenuaed vital statistics
make it difficult to determine genetic changes.
It is certain that tnere hava been
ao abnormalitics in the first generation of babies.
The unmiesirea) Ne aspects for
gonetic studies are in part offset by the teniency of conaanguincu
are prevalent among the Marshallese,
marriages that
From this standpoint genetic effacts may
davelop and are being sought.
-
Long Term Pffects of Internally Deposited Radionuclides
The very small amounts of radioactive materials that are d posited internally
are by themselves inadequate to produce serious long term effects.
ject 1s complicated by the fact that the individuals had a sub
from whole body radiation.
‘In addition to the whole body radilati
However the sub-
fa) initial insult
the thyroid gland