one 8 ° . Table 4.10 “ : es . . . Source of data . ' Characteristics ae s* « 2 CHA RACTERISTICS ‘OF AVAILABLE DATA ON THE HEMATOLOGICAL, EFFECTS OF PENETRATING RADIATION Japanese rLe si Bombings") Clinical “as Radiotherapy Small Small - Large Large Goud Very good Numbers in Groups Large Serial Counts Count kg 1 Pechniques* Chance of bias duc to simpli techniques No | Fair Yor Fair Yos Good Large Lurge Large Sinall Small Yos No Yeu Yes Yes Intecnal contaminition Additional traumiu None None Nont Minimal Note Yes No Yes Yeu Nu No No No No Yes Gamma, Hard x rays, Gamma, neutrons, x rays, betaa Gamma, beta to skin Hard x rays, gamma Adequacy of Controls “Normal”’ individuals (burns etc.) Species extrapolation necessary Type of radiation Poor Poor Fair gamma some neutrons Pm i : 5 ot ' Goud Fair Poor Dose rote Instantaneous ~5r/min instuntaneous Varying, Body region Total body Usually partial body Total and purtial body Total body Total body; beta to skin Dosage Range Sublethal & Subicthal Sublcthal & Sublethal Geometry Nurrow beam Narrow beam Narrow beam _ 360° field Depth dose curve Iethal Moderate fall Variable lethal Rapid fall off , ~10r/min ~5r/nr . = -: ivthal Nurrow beam Variable‘rapid Essentially fall off to flat flat | pes — Sublethal & __ off . Yes Yes Yes Usually no Yes : e cou \ | / > Good Single exposure * Yous Cand Yor Canad Poor Dosage estimation . Large Antinnls el Exposail sage ge e Marshalles Laboratory cdl OO dhrtane g veo Accidents be ee . eo a: oa *Same technicians for all counts; rigidly standardized techniques throughout etc. } Table 4.11 MEAN PERIPHERAL BLOOD COUNT VALUES FOR SEVERAL CONTROL POPULATIONS (x 104) ‘ : Source of data Determination 1947-19488 1948-1949" Total White Count Neutrophiles Lymphocytes 9.9 5.5 2.9 0.6 0.9 9.5 5.0 2.8 0.6 1.0 Q.1 Monocytes Eosinophiles Biasophiles Platelets , anunean Japanese Kure, Americans®?* 7.4 4.4 2.5 0.3 0.2 0.0 Kwa}American Miujuro Controls Controls 7.0 4.3 7.8 4.1 9.7 4.8 2.1 0.4 0.2 0.0 3.3 0.3 0.3 0.0 4.1 O.2 0.5 0.1 Americans 250t 238 308 *Age 21 years tThe mean value fur 50 normal young American men, using the technique employed in the present ‘ ; ; ” study was 257,000 t ' ' ‘ ‘ : i t ate a -¢ ee