Radiation workers, however, are never under ten years PHOTO FROM “MEDICINE” MAGAZINE old, nor often over seventy. By their relatively small num- bers, they do not represent a fair sample of the diversity of mankind. Just as there are some people who have been found unusually sensitive to sunlight, so there must be some who are more sensitive than others to radioactivity. For such reasons it has been considered desirable to set the tolerance dose for the entire population lower than that for medically-controlled radiation workers. Typically, the maximum “permissible’’ dese for occupationally exposed people is reduced by a somewhat arbitrary factor of 10 to obtain the maximum “permissible” exposure for people at large. By such a standard, the general population ought not to receive more than about 30 rads per lifetime. or roughly four times the U.S. background radiation. This does not mean that such a dose is guaranteed to be safe, or that it will produce no damage. On the contrary. it implies accept- ing as socially tolerable some genetic damage, which can be estimated only very roughly because of our poor knowl- edge of human genetics. Estimates, nonetheless, have been made. The U.N. Scientific Committee on the Effects of Atomic Radiation, for example, has attributed to one rad, from any source and applied only once to a single generation of the world’s entire population, the capability of causing ultimately 100 to 4000 defective births for each million of the population. The percentages are small (between 0.01 per cent and 0.4 per cent} and the range is large (a tacit admission to the inexactitude of our knowledge). But when applied to the world’s population of about 214 billion people. half of whom are assumedto be below the mean reproductive age. the total number of defective births will range from 125.000 to 5 million,* spread out over scores or even hun- dreds of generations. These defectives may not be discernible from among the much larger number of cases which are a result of other unknownfactors. Assessments can also be made for the somatic damage induced by radiation. While there is common acceptance of the inevitability of genetic damage, however, there is no such agreement regarding somatic damage. Many scientists believe that a radiation threshold exists for so- matic effects, that we have not yet exceeded this value, and therefore that no somatic damage (cancer, leukemia, short- ening of the life span) can be attributed to the low levels of radiation to which we have been exposed so far. Other scientists hold to the view that biophysical distinctions cannot be made between somatic and genetic effects and that radiation which causes damage to reproductive cells can also damage any other living cells. No one knows at this time which view is correct. INTERNAL RADIATION In addition to the radiation received by the body from without, at least three substances contribute their radiation from within the body, and have done so since there first *A conservative estimate, based on the assumption that the world population will not increase. “Hot spots” in thigh bone of a woman who worked with radium some 30 years earlier show up dramatically in photograph taken by means of intense radiations emanating from the honeitself were men: potassium-40, carbon-14, and radium and_ its radioactive decay products. Carbon and potassium are necessary components of life; they are fairly uniformly distributed within the body and from person to person, so it seems not unrealistic to be guided by the tolerancedose information developed in our studies of external radiation. It is plain that potassium-40 (which contributes about 1.5 rad per 70 years) and carbon-14 (about 0.1 rad per 70 years) have not added much to the natural background radiation. But radium is another story. It plays no knownrole in the life process; it is present because it is widely distributed in the soil and rocks. It is ingested, or sometimes taken into the lungs, and though it is present in very small amounts, its activity can be more important than that of potassium-40 or carbon-14. Radium is not uniformly spread through the body. Because its chemical behavior closely resembles that of the element calcium, constituent of all bone, radium concentrates in the bones. Furthermore, in large doses it does not distribute itself uniformly even within the bones. The bone grows most, of course, in youth. But even the mature bone undergoes remodeling; its constituents are steadily being taken up and laid down again. This means that where radium lodges depends on just what part of the bone is active when the radium enters, and on the whole complex matter of bone formation, growth, and maintenance. The energy emitted in the decay of radium is chiefly carried by particles which cannot penetrate the whole body to reach the outside. They spendall their energy in a distance of a thousandth of an inch; they deposit a thousand times as much energyin crossing a cell as do the rays from potassium-40. The variability of the site of radium also implies its possible concentration in local “hot spots” be- yond the average value (see photo above). A hundred or so persons have been examined who have held excessive amounts of radium in their bones for CONSUMER REPORTS 105

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