12 Ocean in 1954. Fourteen of them were examined under hospitalization, and the other four were treated as outpatients. At first we planned to examine all the exposed persons (twenty-two in total), however, mainly for reasons of their own, we could not include four of them in the 1964 survey. In general, these persons had been in good health during the past years. Although several diseases occurred in some of them, there was no definite reason to relate the radiation exposure to such diseases. Since most of them got children after being discharged from hospitals, it would seem evident that permanentsterility did not occur in them. The routine physical examinations of 1964 revealed that liver was palpable in ten cases. However, it was not cirrhotic, and did not seem to be related to liver disturbances. The routine physical examination had no observation to be normal, although neutropenia, lymphopenia, eo- sinophilia and slight basophilias were observed in one or two cases respectively. N. AP-ase-score decreased in one case. Bone marrow examinations revealed slight increase of myeloblasts and M/E ratio in Cases T-3 and K~12 respect- ively. “ Mitotically Connected Abnormalities ” were found in a few cases. In view of these findings, it could be indicated that there is some residual effect of radiation exposure on haematopoiesis on these persons. Chromosome observations of peripheral leucocytes were made in 13 cases. The average rate of chromosomeaberrations was much higher than that in the normal. The frequency of aneuploid cells was higher, and chromosome-type abnor- malities such as dicentric chromosomes and monocentric abnormal chromosomeswere frequently observed. Cells with dicentric chromosomes occurred in 7 cases, and those with monocentric relatable to the radiation exposure. Residual beta burns of the skin were noted in 13 people of the 18 examined. The burns were abnormal chromosomeswerepresent in all of the observed in wrists, external ears, abdominal walls, to be necessary in the succeeding annual investigations. There were some abnormalfindings in different laboratory studies. However, it was not proved that radiation exposure was related to these results. Whole body counting and determination of urinary excretion of '’Cs and *°Sr were carried out. No significant increase of '*’Cs or Sr was Ophthalmological studies revealed lens opacities in 6 cases, in which 2 cases showed opacities of posterior capsules. However, these changes had not characteristic features described about found on the exposed persons by the examinations. In general, the results of 1964 medical survey foot and leg. Most remarkable ones were those seen in abdominal walls. Skin biopsies of the abdominal walls were performed in six cases. Histological diagnosis as well as macroscopic examination of these lesions indicated no malignant change. In one case that showed complete epilation at the time of the accident, a small alopecic area wasstill noted in the scalp. progressed cataracts of atomic bomb survivors in Hiroshima, although lens opacities of 2 cases were found in posterior. Further ophthalmolo- gical survey should be needed. Haematological survey showed that the results of peripheral blood examinations were almost cases. To trace the fate of such cells with chromosome abnormalities persisting in them seems on Japanese fishermen did not indicate clinically significant late effects of the fall-out exposure in 1954. However, it seems to be very important as well as necessary to conduct further medical survey to detect the significance of subtle changes such as observed in haematological, chromosomal or ophthalmological examinations.

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