SUBJECT: Combined Injury OBJECTIVE: To determine the effects of combined blast, thermal and radiation injuries, TEST PROCEDURE: STATUS OF KNOWLEDGE: No specific field tests have been designed with this objective. Experience at) GREENHOUSE and UPSHOT-KNOTHOLE has given field data, Analysis of the Japanese data indicated that there was a number of combined injuries but the nature of the data made evaluation difficult. Charts will be presented at the conference which show the probabilities of combined radiation and thermal burns occurring in the same individual, a. Burns and Radiation (1) At GREENHOUSE it was demonstrated that "if thermal burns progress to a point of partial epithelialization, healing proceeds in spite of mortal radiation injury. However, granulat- ing biopsy wounds or burns become gangrenous or slough when ' signs of radiation sickness develop". KNOTHOLE was similar, (2) Experience at UPSHOT- Laboratory experience at Medical College of Virginia in 1950 indicated synergism. Small, non-lethal contact burns gave a high mortality rate when combined with non- lethal amounts of radiation. These results were only partially confirmed in the past year. Radiant energy burns apparently produce a milder systemic effect and therefore a lower incidence \ of mortality when combined with non-lethal radiation. (3) Recent work at the Naval Radiological Defense Laboratory with hot water burns was similar to the contact burns at Virginia. Radiant energy burns have not been fully analyzed as yet. b. Fractures and Burns Combined fractures and burns have been studied in The results indicated that plaster casts may be contra- dogs. indicated in the treatment of fractures with overlying burns. Intranedullary nailing even though the burnwes more satisfactory. The applicability to humane has not been evaluated. c. Radiation and Surgery Surgery (resection of bowel) following radiation had no effect on either the recovery from surgery or the course of the radiation syndrome, 3t

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