#"inetantaneous fraction of atous: decaying per unitdatag
yet
int
at
tt.
instantaneous fraction of atoms removed from compartment. i by
adiwollot
see
18 pipe Nee ae
1
"ate
initial atom ingagtion ‘ate, 7avons,dey},
acinmay jads
1 omly
physiological nechanisus, day”
at,
Je Vaiviton evosaninetant arf:
:
a
<<
’
wt
Xi = ‘compartment i deposition fraction,
rae
va
the number of vatdgen*tdlpgremqnt\L*aélagiye, fo the number in all
moat
At
TP emt
tp vtivivss euosnstiuas. “Ud
t
instantaneous ‘urine activity. concentra tion, Bq gi?
al L gudsut Hee
= subject urine exgretion rate, & day” 1,
fraction EromGlyFeast i to reese Age
yf
= fraction excreted,‘by the urine: pathway,
dads: @wolieat
‘o?Y YK
|
T
‘|
be
5
= instantaneous fraction of stone removed or added to the: atom uptake
an
x
1
ro
cca:
conpartwente asthe onset of declining continuous uptake, (t*0),
cutter
addon
|
aee Pty sy
. taygad
{
%
perunit. time, day”!, due te dadeors*Sther Chanendoubbive ‘decay,
au
v4
f ove 4
‘
di
instantaneous body burden, My
i.
» Sf omarys
agetog
.
ted
syndy tay
74
bang
uninitoh
bank}
ysaege
Teue Saat
it
= body burden at the onset ‘of‘uptake, ‘ia,
a
o
A
2
. A
uu
the number of disintegrations in all compartments occurring‘during
the uptake interval, Bq days,
2
Co pd RES
The development of Eqs. (1), (2), and (3) was based on the following convo
lution integral.
Re
At some variable time, T, defined during @ fixeduptake
interval, T, the daily activity ingestion rate crossing the gastrointestinal
-
any
tract to blood is given by
Af P eo e
~Ckgth)T