weep te : : ye Barly offects of exposureof animale and’ man to high leveln of radiation from sources external to the body 1. Gamma and x-radiation ~ syndrome of radiation sicknonn e. Fellout on varshallese: Rongelap, Uterik db. (Los Alamos inoidents7) 2. Re Beta radiation - burns a. Marshallese b. Other examples, human boingn and enimals Possible eerly effecte of exposure to high levels of radistion fron radioactive materials within the body (fxeuples7) Delayed effects dus either to single wansive dosea or to protricts! chronic exposure; enumeration of effents of interost; dose depenien > D. Genetic effecte 1. ° Sumary of the nature of genetic effects (Supplementary waterial should be inoluded in written statement) 2, Relationship of radiation offects to natural mutation (a) Predicted increase in mutation rate as a renull of antimated increase in radiation levele from fr} inut. 3. ¥.. Effects on population: as individuals and as a wiole Aplastic ansnis, leukemia, and cancer an a result of expomra radiation 1, Human and enimal experienne JCAE 2, Desep at vbich observable darnge cccure; relations} of prohahility of damge to dose cnd dore rate; latmt parsote: doubling doses; relationship to tienve irradiated 3. Relative importance of cancer and leukemia under var{oun conditions: external source; exposure of various critics} nente st

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