Number of Spermatozoa (mm?) lowering of motility and morphological abnor- malities of spermatozoa were also observed. The testicle of the fatal case, which died 206 days after the explosion, was remarkably atrophic. possessing the interstitial tissue composed of loosely arranged connective tissue. Spermatogonia were greatly decreased in number, and in some areas they were completelylacking. No sperm was encountered within the lumen of either seminiferous tubules or epididymis. Indications of recovery were observed at about Fig. 5. 5 and Table 2). 1954 1 | , 1955 M (2) | M M M M aa (| 1957 1958 Changes in the Number of Spermatozoa | | 1959 1960 ff 1961 | 1962 | 1963 | 28 30 28 f 27 26 22 f f 25 m m 25 f 24 M m f 22 f 26 18 M m M f 23 m 22 f 24 23 f I 1 . . : M (3): M (2). M.--e- Marriage Meese Male ,,Age in March 1954 27 38 (3) (2) (4) (3) M 13 +14 15 1959 Marriage and Childbirth of the Patients 1956 | 1957. 1958 A 1956 ¢ M M | f f M m f A if 18 22 39 | Jenene No. of children at the time of exposure ap venees Fatal case farses Female A. Abortus m 27 20 RTaee | SPTa 1955 5. Liver Function Slight disturbances of the liver function were found in a few cases about 4 weeks after the initial exposure. Later it became more obvious, i.e. the repeated appearance of jaundice in several cases, an increase of serum gamma-globulin con- Most of them began to reveal a sign of regeneration about 2 years after the exposure, and got children (Fie. Date 0 l= normal value in all the cases. -— 1 1954 one year after the explosion in some patients, but number of spermatozoa wasstill far below Table 2. 3 spermia was found in [6 cases in November 1954, e.g. about 8 months after the detonation. Both