-
oe
Ae en ae ee allele bes ares ett bree
aa en er
It was then alpha countea, (79)
secticns of Illinois in which the Ra“? skeletal levels in the population
are 10 times those of their neighbors.
pae2o was determined by the radon emanation method of Lucas, (22)
The differences are caused by
The ash content was determined from the calcium, expressed as calcium
variations in the pae®® concentrations in the drinking water, (2)
RaD is another such nuclide.
phosphate, which, because of a series of compensating factors, is equivalent
As shown in Fig. 1 (Slide 1}, RaD is
to the ash. (9)
\
a pav“o decay product, but one does not expect it to follow the parent
because of their different chemistries and the long half life of RaD.
III.
The most important difference is that RaD is derived from the rare gas
:
2
:
4
Interpretation of these measurements to obtain meaningful
*
conclisions involved certain problems.
intermediate, n° 2 which is easily translocated from the parent Ra??o
Only in the lust fev years has naturally occurring RaD been
studied.
representative of the whole.
Considering the amount of information
Thus,
7
compared to the subsequent measured values of piack’?) of iii (8) and
ol this
Hursh (10)
using small sections cf bone.
On the other hand,
was from a single individual.
(Slide 2).
Data from 8 sets are shown in Table I
Within a facvor of 2 or so (with a few excepvions) any given
pone appears to be representetive.
Experimental Technique
of Rab, ReF and pae26 in human specimens.
|
These consisted of surgical
|
and autopsy specimens of soft tissue and bone obtained from medical
sources.
.
that a given bone represents the total skeleton {as defined by a few
samples}, and for lack of a better hypothesis, it has tvzen assumed tnat
RaD.
Next, the nitrates were
The results in Table 3 (Slide 4) show about SO% of the activity
to be in the skeleton, a resuit also in agreement with that calculated
destroyed by repeated fumings with hydrochlorie acid, and finally, after
from the wietabolic parameters of stable lea q,
was pluted onto a silver disk at g0° ¢.
412,15)
Sinee the skeleton
constitutes about 10 to 15% of the total body waight, and contains more
-2-
<TR neg
Because of the fairly high probability
The second problem considered was the whole-body distribution of
The analyses were performed by first wet ashing
10
with a few notable exceptions.
the distribution of RaD is wniform within the sxeleton,
The RaD was determined by analysis of its decay product Rar (po?)
the samples with nitric and perchloric acids,
Table 2(Slide 3) shows the Rae"
concentrations to be relatively constant within’a given individual, again
vor this study particular effort was devoted to the determination
adjusting to pH 0.3, the Po"
Thi. was dane by the use of sets of bane sections,
tibia, sk 41, mandible and either rib or joint bone, in which each sat
measuring whole body asn, found the RaD content to be only
(Fig. 1}(Slide 1).
it was necessary to determine how well they represented tne entire
Skeleton ard body.
abour 1/2 tnat of the Rae? |
Ii.
Only small samples were available and even
if larger ones pad been available, processing would have been difficult.
available at that time, this conclusion was quite reasonable wher
laboratory (9)
The first, was that of the
sampling procedure, that is, to determine if a particular semple is
Dudley, ‘° estimated the body content of this nuclide tc be
about 10 times that of Ra@"°,
Results and Discussion
x
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i