- 20 #

.

*

In the context of his comment it is interesting to
refer to the National Academy of Sciences,

National

Research Council report of 1961 on the Effects of
Inhaled Radioactive Particles. [{c] The first
sentence reads, "The potential hazard due to air-

borne radioactive particulates is probably the least
understood of the hazards associated with atomic

weapons

tests,

production of radioelements,

and the

expanding use of nuclear energy for power production."
A decade later that statement is still valid.
Finally

let me quote Drs. Sanders, Thompson, and Bair from a
paper given by them last October. [d] Dr. Bair and

his colleagues have done the most relevant plutonium
‘oxide inhalation experiments.
"“Nonuniform irradiation
of the lung from deposited radioactive particulates is

clearly more carcinogenic than uniform exposure (on a

total-lung dose basis), and alpha-irradiation is more

“sf

carcinogenic than beta-irradiation.

The dceses reguired

for a substantial tumor incidence, are very high, how-

ever, if measured in proximity to the particle; and,

again, there are no data to establish the low-incidence
end of a dose-effect curve.
And there is no general
theory,

or data on which

to base a theory, which would

permit extrapolation of the high incidence portion of
the curve into the low incidence region."
I agree and
I suggest that in such a circumstance it is appropriate

to view the standards with extreme caution. 31

{c}

U.

S.

NAS-NRC Subcommittee, Effects of Inhaled Radioactive

Particies.
Report cf the Subcommittee on Inhalation
Hazards.
Committee on Pathologic Effects of Atomic
Radiation.
Naticnal Academy of Sciences - National
Research Council, Wasnington,

848,

(a]

NAS-NRC/PUB-648, 1961.

D.

C.

1961.

Publication

Sanders, C.L., R.C. Thompson, and W.J. Bair,

Cancer:
In:

Inhalation Carcinocenesis.

Division,

Proceedings of a Biclogy

Oax Ridge National Laboratory,

conference heid

in Gatlinburg, Tennessee, October 8-11, 1969.

Hanna,

"Lung

Dose Response Studies with Radionuclides."

Jr.,

P.

Nettesheim,

and J.R.

Gilbert,

M.G.

|

eds.,

U. S. Atomic Eneray Commission Symposium Series 18, 1970.
pp. 285-303.
(CONF-691001).

31/

Geesaman,

Donald P.,

“Plutonium and Public Nealth,"

>}
Lawrence Livermore Laboratory, Calif., GT-121-705,
Avril 19, 1970,

reproduced in Unterarciund Uses of Nuelesr Erercv, Part
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