-~ 17 n t It would take 53,000 particles of the Size illustrated in Table III to reach the MPLB of 0.016 uCi which results in 15 rem/yr to the entire (1000 g) lung. However, as Table III indicates, these particles would irradiate only 3.4 g of this 1000 g to the lung, but at a dose rate of 4000 rem/yr-°. Thus, as Table III indicates, these particles result in an intense but highly localized irradiation. fundamental question is, then: oF A is this intense but localized irradiation more or less carcinogenic than uniform * irradiation? Alternatively, is the DF for this particular form of irradiation equal to, greater than, or less than one? In the remainder of this section, we review the guidance, or more appropriately lack of guidance, for dealing with this hot particle problem. 22/ Geesaman, Donald >., UCRL-50387, pp. 8, 15. 23/ Langham, Wfight H., The Problem of Larae Area Plutoniun Contamination, U. S. Dept. of H. E. W., Public Heaith Services, Seminar Paper No. 002, Dec. 6, 1968, p. 7. 24/ Long, A.B., "Plutonium Inhalation: The Burden of Negligible Consecuence,"“ Nuclear News, June 1971, p. 71. 25/ Geesaman, Donald P., UCRL-50387, pp. 8, 15. Based on Geesaman's mocel for a lung at one-half maximum inflaticn. GeeSaman estimates a total of 68 alveoli at risk, each 8x1076 cm3 in volume, and deep respiratory zone tissue density of 0.12 g/em>. 26/ See footnote 23. 27/ Based cn a lung mass of a standard man = 1000 g. mis Ac assumes : that the radiation field of the 53,009