od arte ap apes *

data, such as -4 Gurhips between T, and age,

the Marshallese pec
with a value of 70 days
reported (5).
The data of Miettinen suggest an sverage
value of about 70 days for the ages 16 through
75 years. Lists of “age limits” indicate most of

:- s@utthood is reached” (1). Other investigators

age. Whether the inclusion of individuals of

a age

ACX, OF Speci -...’ pilahas said, “If there is a
chanze of hal- dife‘with age then it presumably
stamee at bith and imcreases steadily until
indicate a stranger support for a relationship
between T, and age. Bengtsson et al. state
“Fn: results also confirm that biological half-

these individuals were Jess than 50 years of
ages down to 16 years has the effect of Jowering the average value of T, for these groups

compared to data on

groups of “adults”

. #m.« for cesium increases with age” (12). , presented by Rundo and Hansen and others, is
‘Onstezd et al. report that in their studies in- (’ not known. Possibly other biological and

ser children, perhaps by a factor of three

2 five.”

The Federal Radiation Council, in its Report

Wo. 7, <19) stated:
“The data for persons younger than 25
years suggest that the biological] half-life
becore maturity may be a function of age.
Biological half-lives of about 20 days or
tess have been reported for infants. For
this report a value of 30 days is used as
the biological half-life of cesium-187 in
infants.”

A value of 30 days for infants appears to be
a conservative assumr‘ion since the available
data for infants show values close to, but below,
‘thir value.
;

Considering the available values of T, for
the entire range of ages in the population, the
trend that is suggested for T, and age may be
presented graphically. The solid line in figure 2
is drawn to account for the apparent rapid
change of T, with age for those less than about
25 years of age, to provide an average value
of about 80 days for younger adults as suggested by Boni’s measurements, and to provide
an average value for adults over 25 years of

cage of about 100 days. Considering all age

‘groups, the solid line in figure 2 develops an
average T, for all ages of about 75 days.

120—]

Bete Approntngiion seeamieemmemnsan
> 12.0617 6 omtpmimemce

§

<78) contains the following:
“This value is almost certainly too large

Model development

t.

Strontium-89, Strontium-90, and Cesium-137”

environmental factors are more important.

i

voxing more than 6,000 individuals,
our findings suggest that, within a single
spc cies, biological half-life is dependent on
age” (17).
an referencing the use of 100 days for the
‘gkiogical half-life of cesium in man, the
December 1964 report to the Federal Radiation
asuncil by the National Academy of Sciences
Advisory Committee, entitled “Implications to
Maun of Irradiation by Internally Deposited

OLOGICAL MALF-TIME (aay)

ude GY Shete ate
+ hw

* Guarded state ne is,by B( ) investigators
- indicate reservcation: ’ “apecifying trends in the

Boni's value of 81 days, which is applicable

ior adults 2% to 40 years of age, is in close
&greement with the average value of the lower

SO nage ee MONREL ERE ENE Me mE Nec

Ntewomgpnten ner

Aimit for adults for all investigators of 78 days.

However, there are little data for ages within
the category specified as “adults” to determine
if there is a trcnd of change in T, as a function
of age above about 25 years. The average value ©
far adalts for all investigators, those that
Specified a range of values and those that did
“ao, is 101 days. The most data for an early

saidy for all ages in a population group are for

~—_—_}—_4

" 4

i

“

AGE tynen}

+——2

Figure 2. Biological half-time versus age

The three segments of figure 2 may be

approximated by:
where:

Ty = 12.8 (x!+-e-*)

(W)

T= biological half jife (years)
x=age (years)

@ecember 1965

_

__

422% ajo8| PODS

Select target paragraph3