The Laboratory’s efforts in the early 1960s were directed toward understanding injury due to ionizing radiation. The ; Radiation Laboratory began the use of radioisotopes regularly in the treatment of disease in 1936. Of particular interest was the study of any delayed effects of radiation and the incidence of cancer. The genetic and subcellular effects of ionizing radiation were also studied. The Berkeley Health Physics Group conducted regular procedures for collecting and analyzing radiation samples of the Laboratory accelerators, using various neutron detectors and monitors. An extensive series of measurements were made at the NTS during Project Bronco to provide better estimates of the radia- tion exposure due to neutrons at longer distances from the source. Beginning in 1963, the Livermore Biomedical gated the effects of radiation on humans. Program investi- A major effort was the development of theoretical models to describe the behavior of chemical elements in biological systems and the development of computer systems to process and analyze such data. In the late 1960s, the Biomedical Program began the study of radiation on DNA molecules. Plowshare Program The Plowshare Program was conceived and initiated at the Lawrence Radiation Laboratory during 1956 and 1957. The Laboratory explored the use of nuclear explosions for earth-moving excava- tions and other engineering projects. At the time the program was initiated, possible industrial applications centered around excavation since a number of craters had been made previously-one up to 1,000 feet in diameter in the atoll reefs of the Pacific test site. Scientists and engineers envisioned nuclear excavation as a possible method for constructing harbors and canals, including a harbor site in Alaska and canals across the Panamanian isthmus. Scientists found that explosions conducted underground generated large permeable zones which provided pos- sible applications for waste disposal, aquifer recharging, ermal energy. gas and oil oil and gas storage, stimulus, A few nuclear tests were conducted and recovery of geoth- in basalt and desert alluvium. In July 1962, the Plowshare program carried out a 100 kiloton (kt) event in alluvium at the NTS. Three nuclear cratering experiments were conducted at NTS in this period: Cabriolet in hard rock, Schooner, and Buggy, the first detonation of a row of nuclear charges to excavate a ditch. The greatest problems with cratering were the stability of the resulting slopes and radioactive fallout. In the 1962 shots, experimenters were able to reduce the amount of fallout released to the atmosphere from the earlier (Cabriolet) to later (Danny Boy) shots. As a basic

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