DR. SHILLING next) introduced Dr. Max Zeille to discuss the genetics program. GENETICS DR. ZELLE pointed out that he observed a distinct change in point of view and emphasis since his last term of office with the Division six years ago. He saw the increased interest as an opportunity of exploiting radiation and isotopes in studies of basic or fundamental genetics. He observed that this should not interfere with the primary objective. He spoke of an attempt being made to extract additional data from some of the early large scale studies sponsored by the Manhattan Engineering District. DR. ZELLE spoke of the work being done at Oak Ridge and at the Argonne National Laboratory. He spoke also of suggestions which had been made by Dr. Sterling Emerson shortly before he left as to areas in which there should be more emphasis. These include certain aspects of consanguifious marriage studies, surveys of children of parents who had received known radiation exposure, increased support of human genetics in medical colleges, studies cf radiation on nuclear proteins and studies of the chemical nature of genes and other self-reproducing cellular constituents. DR. EMERSON also believed that fundamental genetics studies should be increased just to learn more about mutation and also a study to determine the radiation induced mutation rate in other animal species than the mouse. In answer to a question by DR. WARREN concerning studies in Japan of consanguinous marriages, DR. ZELLE said that it was expected that it would take two years to gather the data and two additional years to analyze them. After Dr. Zelle's presentation, there was considerable general discussion by Committee members and Dr. Beadle on the subject of genetics. DR. SHILLING then introduced DR. PAUL HENSHAW, who spoke on the subject of human radiobiology. He spoke of the NCRP Committee studying radiation injury with which the Division had been cooperating. He also discussed the efforts being made by Dr. Karl Morgan's HUMAN group at Oak Ridge to give attention to more accurate RADIOBIOLOGY dosimetry with respect to the ABCC cases. This involved certain studies being conducted at the Nevada Test Site. DR. SHILLING then introduced MR. HERBERT TALKIN, who spoke on plans for future dosimetry studies at the NTS. It is planned to duplicate or stimulate the Hiroshima or Nagasaki bombs and obtain more accurate dosimetry in Japanes=type houses which were to DOSIMETRY be constructed. There had been preliminary studies made AT NTS during the current series in two Japanese-type houses which had been constructed. DR. WARREN inquired as to whether there had been a continued heavy rate of attrition as far as the ABCC patients were concerned. DR. DUNHAM stated that there is much better cooperation with the Japanese at the present time. DR. CANTRIL asked if continuing attention was still being paid to the induction of thyroid cancer secondary to the treatment of hyperthyroidism. Although there had been no evidence of the development of cancer in patients treated with radioiodine, he expressed the opinion that this should be followed further. = Fu j

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