It was generally agreed that the discussion of Item 2 had been included with Item l. RESEARCH PLANNING (continued) Item 3. ORGAN SYSTEMS - DR. CANTRIL asked how well this program was being coordinated with work of the Aircraft Nuclear Propulsion program and DR. DUNHAM told of work being done by Brookhaven in the study of brains of animals which had been taken up to high altitudes. Item 4. PERFORMANCE AND LIFE SHORTENING - DR. DUNHAM explained that the Division planned to intensify these studies, particularly as far as life shortening studies and aging, and planned to cooperate closely with the NIH, DR. WARREN expressed the opinion that the AEC had a responsibility to the Armed Forces and should investigate the influence of acute doses of radiation on the ability of men tc carry out assigned tasks. DR. DUNHAM spoke of the work that was done a number of years ago on dogs on treadmills showing very little impairment in work capacity. There was also work done at Austin, Texas and at Los Alamos. DR. CANTRIL suggested that the best correlation with that type of research could probably be obtained through nuclear weapons tests, although this would be expensive. DR. BONNER spoke of a preliminary proposal from Convair to design a reactor that would emit, a pulse of radiation essentially equivalent to that from & weapon which would be useful in working out some of the domimetric problems. This however, would cost about $700, 000. DR. CANTRIL expressed the opinion that such an installation would be useful for many other experiments besides biological. DR. WESTERN told of the interest of the FCDA and the ODM in determining under what radiation conditions people could be brought back into radiation areas after an atomic explosion, and in determining the length of time during which they could staythere. This would appear to have very important civil defense implications. DR. DUNHAM stated that he did not believe any experiments had been directed at that problem and DR. WARREN agreed that it was a very important one to explore. Item 5. COMBATTING DAMAGE - DR. CANTRIL spoke of Dr. Bruner's statement that there was now skepticism over the possible long-range benefit to be derived from the humoral approach and inquired if the work of Jacobson and that at Parke Davis were still going on. DR. BRUNER stated that this work was still in progress, although he had not covered it. He also mentioned work at the Rand Laboratory and at Roswell Park. DR. DUNHAM spoke of plans to make available a contract for $50,000 to Armour to protect the Government's patent rights. DR. SHILLING spoke of the Werthesen contract at Southwestern Research Institute in which they are searching biochemically for an active principle from the serum from pregnant bovine. - 1D.

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