US DOE’ ARCHIVES
326,U.S. ATOMICENERGY
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22 Jamary 1955
Morrig Inn
“Notre Dame, Indiana
wee
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B86ret Oredhar (HTED, Rugene Cronkite (NERD), Charles Ounhan SET)
gers
TI. Noblaons Jordon (LORUND), Joa Tevtend
(0.
of 7
Dun.
“ore beloe tle OF Chicage) , Thomas Luckey (LCBUND), G, Philiip Uilier (0. of
“eaee!, Tecer Reid (OMR), James Reyniers (LOSUND), Tiliies Semiere LoDUD),
Jy v. Shilita: (OMS), Philip Trexler, (LOBUND), Morris Wagner, {LCDiST),
Clr of Meobiacs 3320 9.5, to 3:15 PLE . (including lunch hour).
ig Meovines James A. Reyniers served 23 chairman and cach mentor
‘4
Pero % OSaF eee Progress
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et “ALLOBUNG Advisory Catumiciyge
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Report to date preparad dy"she LOREM soot?
SOND sont over tha dcto gith the manbers of the Gormitsce
13 vere supplied by other members of LOBUND Tuctituss.
nsicersable discussion on many phases of this sroijocs and
Ruport, the following contlusions vers in order:
Gonclusions:
» Additional anirvala in the 400 and 600 r rangs are te be run along
ith contre 13. it vas boliavedé thet six additional germeiroe aninals
fn gach of these groups vould probably be sufficient to make tho sssults
gignifioent. IY the individual experiments contain six or more germeirt
oninaic, thoy chould be squnlly divided between 400 end 6CO r. Survivel
is to be obsemred to 30 days only. Depending upon the vesults vith thess
additional animaic, the axact number to be run will be dctaomained oy LOSUND.
ore
goes
Se
ee ef
ho folleving observations and studies will be omitted from the
ezperiments plnnacd in (1) above:
homatology and prothrombin time.
5S.
diarrhen, agonal pericd, bodyreight,
The 800 r croup is completed and the results are siznifisoart.
4, Tho hemorrhagic patterns should be more closely studicd by soupsring
pairod killings of irrediated germefree and irradiatcd conventicnal rate.
Colored photographs of these findings should be obtained if at all possible.
5.
No doiiberately contaminated experiments should be run until the 400
and 6CO r groups with germefree aniteals are complsted.
6. All radiation experiments on accidentally contaminated animals
should begin 14 daya after a positive culture is obtained. Histolegical
examinations should be carrisd out on these animals.
7.
Further work on the use of streptomycin in rats is not indicated,
8. It vas agreed that until the 400 and 600 r germefres groups ere
completed that a specific recommendation from the Committees for future
experiments should ba held in abeyancs.
Minutes by R. F. Ervin
BEST COPY AVAILABLE
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