Table 2
72-h culture:
Chromosome abnormalities in peripheral lymphocytes of the fishermen,
data from 1965 to 1967.
cases
examined
No. of
cells
analyzed
Aneuploid
Control
10
693
2. 88
Fishermen
13
881
2.05
Fishermen
15
1102
2. 90
Fishermen
1967
16
1248
2. 48
10
750
2. 27
12
950
2.00
No. of
Cases
1965
1966
48-h culture :‘
Fish
| 1965
Fishermen
1967
cells %
i
|
unstable
Stable
cells %
(i )*
0.14
onl
cells %
(/)*
i
i
0.14
\
(1/10)
(1/10)
(9/13)
(3/13)
(14/15)
(5/15)
first signs of regenerat
with following
;
posure,
So
0. 46
2. 23
3.45
2. 88
(15/16)
The hematologic
0. 45
1954 were reported *
0. 56
(6/16)
the
dose soon a ne
1. 20
(6/10)
0. 67
(4/10)
(9/12)
(6/12)
Generally speakii
sons. should
findings. From*bi1S }
to decide the theral
As to the Jap
0.74
2.11
abnc
and morphological a
tions of recovery were ‘
necessary to detect
mat«
observed in he
* Number of cases showing the abnormal cells per total number of cases examined.
so high (Table 2).
2. Unstable abnormalities such as dicentrics, etc. were observed (Table 2).
3.
The frequency of stable abnormalities was remarkably higher than
in controls (Table 2).
4. The detailed analysis of stable cells revealed that stable abnormalities
were divided following 3 types:
a. stable cells with balanced chromosome constitution... 67 per cent
b.
c.
5.
stable cells with deletion of a chromosome .:.29 per cent
stable cells with excessive chromosome material...4 per cent
In 3 cases small chromosomes which are similar to the Ph! chromo-
some were found.
.
.
.
.
6. The examined fishermen wereclassified in3 groups according to the
degree of the injuries indicated by the minimum values of neutrophils
shown shortly after the exposure. It was found that the mean valuesof stable
and of unstable cells were higher in proportion to the extent of the initial
damage.
Minimum values of neutrophils roughly corresponded to the estimat-
ed external radiation dose.
tem
=>
eee tte mn
-
Hematological
T. KUMATORI
70
4
Amano, 5. (1953) :
Gakujutsu 5
Anprews, G. A+
Diagnosis *
Organizatior
Cronkite, E.P-.
lonizing Re
Washingtol
Guskova, A.B.
Conferenct
New York.
Hasteruk, B.
Conferen¢
New York
HEMPELMAN, ~
Medicine
7. Chromosome abnormalities in bone marrow were observed in 5 cases.
All of these abnormalities were limited to stable abnormalities. While stable
cells in the peripheral lymphocytes showed various karyotypes of their own,
these in the bone marrow were limited to only a few karyotypes.
ISHIHARA, TIsnmmana, T
North H
i T-
SPERMATOGENESIS
Janmers
As a generative tissue, spermatogenesis has many similarities with hematopoiesis. Therefore, the changes of number of spermatozoa is described for
einitate
Kimura, K.
reference. The number of spermatozoa decreased, and minimum numbers were
obtained in 16 cases about 8 monthsafter the exposure.
Lowering of mobility
1, T-
Influer
the Fr