Neeee
Sixty foxholes ~- 2, epen foxholes (()- Fig 1), 24 two-thirds clesed
foxholes (¥ - Fig 2) and 12 off-set foxholes (0- Fig 3) will be pesitionsd
from 5 yards te.40 yards frem ground zero. At these distances it is.
calculated these fortifications will receive inside 25,000 rem <= using a
weapon yield ef 10 tens -- spread frem 5 to 20tens. There are five M~li6
tanks positioned at 25, 35,
45, 55 and 65 yards frem ground sere. Two M-59.
armored personnel carriers are positiened at 60 and 70 yards from ground
sere. These armored vehicles are pesitiened such that the calculated dose
delivered inside the vehicle is 25,000 rem. Each of these shelters will
centain ene instrumented pig (See Appendix A), and ethers if available.
Te evaluate protectien for the user, animals are stationed in open
pens at 650, 700, 750, and 800 yards frem ground zero.
Simple clinical
evaluation fer a minimum ef 21 days pest-exposure is carried out.
Sub-pre,ject 2.2. Three hundred and sixty swine.
te 90 pounds
Swine weighing 70
are exposed on twe axes from greund zere in such a fashion that
one axis (seuth) is te receive a high neutron flux <= gamma ratio dose (3:1)
and the ether (west) is to receive a lew neutron flux —-- gamma ratio dose
(1:2).
(See D. Shot Participatien)
The animals are exposed as on previous
field experiments in aluminum cylinders sat 15 yard intervals on the west
line and 20 yard intervals en the south line and at such distances that the
animals exposed receive from 300 = 700 rem in air. There are fifteen
points on each line and ten of the fifteen points have three internally
dosimetered animals (Appendix A) te cerrelate with measured air dese.
After
expesure the animals are ebserved olinically fer a minimm period ef thirty
days.
Swine receiving lethal levels of radiation will be observed at feur
hour intervals, and all ethers are observed on an eight hour schedule.
These animals which have been altered by having been internally
dosimetered are evaluated with peripheral white bleod count (WBC) and
differential.
Examinatiens are made pre-irradiation, fer back-greund, and
at least en the 2nd, kth, 6th, Sth and 10th days after expesure to the
weapon. Additienal counts are made up to 21 days pest-irradiation dependent
upen the respense ebserved during the 10-day pest-irradiatien period. All
WBCs are by the "pin-head" technique. In additien a parallel study of the
bleed frem at least one animal from each peint will be evaluated by the
standard chamber counting methed.
All swine are weighed prier te exposure and en the 3rd, 7th, 10th,
sth and 21st days after irradiation.
Irradiated swine fram all stations are ebserved at least twice daily
turbances and other untoward clinical symptoms.
eel
fer signs of epilation, melena, hematemesis, central nervous system dis~ (03°)
Sieur
All animals dying during the observation peried will have as sophisticat-
ed a post-mertem study as is required to esteblish the cause of death fer
suppert of the pregram.
Concomitantly, a control LDcy/39 study is carried out at Walter Reed
Army Institute of Research. Sixt dpinals, ef the same group utilized at