D. Shet Participation. Ideally any biemedical effects program must have a predictable yield to obtain significant data. In addition, to obtain a fractionated neutron- gamma flux a shield is placed on the lew neutron flux axis (west) to get radiation levels that contribute to an RBE program. Because of the requirement to visually ebserve the animals in the protected environment, and te decument with photography, if possible, their clinical course, time ef detonation ef the weapon is such that there will be daylight fer recovery. Because excessive periods without water alters the experimental animal, he tolerates it very poorly, and it contributes significantly to morbidity, and maybe mortality. We position the animals for expesure at a maximum of H - 5 hours. Repeated handling and excessive travelling in vehicles is poorly tolerated by the swine, and if the animals are transported and positioned more than twice on successive days they must be allowed a four to five day peried te recover. In the event the device detoenates "one-point", with resultant contamination ef the area, er the device detonates with an insignificant nuclear yield some animals will be available to participate en an extremely limited scale, within 10 days. F. Instrumentatien. Air gamma and neutron measurements are made on three axes - north, south and west. Swine have mid-line gamma and gammaeneutron chemical dosimeter systems. (See Appendix A) To complement visual observation of lethality in the ).2.]1 pregram a system ef telemetering electrecardiographic {ECG) signals fram fifteen selected swine at the cleser in stations is considered feasible. With this method immediately post-detonation these stations are scanned by receivers and if no signal is returned the animal is presumed dead until visual cenfirmation is carried out. In addition, protected from blast, are transistorized direct-writer recorders recording from each of the fifteen instrumented animals pulse and respiration rates (PR & RR). At this moment of reporting, timing signals are required in support of this program. Present Status. Complete implementation of the experimental plan of Project 4.2 awaits only definitive weapon information and date of detonation. ws ryace mY nF Lire ite

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