The risk factor for first generation genetic defects is smaller than that for cancer mortality (National Academy of Sciences, 1972: NCRP, 1987a), being approximately 1 x 10-4. Furthermore, since no genetic effects have been recorded as yet for the Japanese (Radiation Effects Research Foundation, 1987), (b) Transuranics. it is unlikely that any would be found here. The Brookhaven dose estimates vary Significantly, reflecting the transuranic data which may vary by a factor of 1,000. Could this be “real"? Probably not. To supply the transuranic oral input necessary to maintain the maximum urinary output recorded, it would be necessary to eat 5 kg of clams every day -- or even larger amounts of other foods. Obviously, something is radically wrong, technically or physiologically. Contamination is one possibility (urine collection in the Marshalls is difficult). Or conceivably, an inborn error of metabolism allows certain individuals in the general population to absorb 100 times as much from the gut as that which the ICRP recognizes as normal. It is therefore essential, as emphasized in the Preliminary Report, that the problem be studied immediately. As a start, additional urines should be collected repeatedly from the same individuals under rigorously controlled conditions to determine the reproducibility of results, and which simple changes in life style might affect them. {c) Infant dose. The question of infant and childhood dosage has been raised, and is a sensitive issue. months 0-12 appears to be 0.1 rem. The maximum internal dose for More information should become available by October. According to the ICRP tables, the dose per unit intake is 2 - 3 times higher for small children than for adults, but children eat less so that the two factors tend to cancel one another out. In any case, the observations thus far should not give rise to alarm, but they must be followed up. (d) The foregoing comments apply to the future. But what about the influence of the past? The Rongelap residents exposed to the Bravo shot received an acute dose of 190 rem in 1954; during 1957-1978 they received a chronic dose of 3 rem. My opinion is that the addition to these past doses of something like 3 rem during the next 30 years will not appreciably increase detectable health and genetic risks in a way that should preclude return to Rongelap Island. 41