32
Tabie 16
Immunoelectrophoretic Analyses
Subject Nos.
Findings
Normal
15, 30, 20, 78, 8, 76, 92, 77, 9, 14, 33, 16, 2, 21,
57, 47, 4, 37, 10, 73, 12, 914, 835, 838, 875, 844,
865, 896, 982, 836, 832, 936, 955, 956, 957, 830,
960, 939, 893, 979, 840, 833, 915, 967, 975, 882,
898, 1005, 868, 822, 1042, 841, 825, 885
Slightly increased y globulin precipitation-line
53, 71, 86, 52, 63, 22, 32, 87, 59, 54, 79, 6, 66, 1,
45, 928, 856, 883, 940, 1036, 944, 992, 858, 813,
864, 853, 887, 942, 829, 820, 828, 924, 961, 969,
895, 855, 884
Markedly increased y globulin precipitation-line
862, 891
Slightly increased precipitation-lines for 6,,, 4,,,, and y
34, 75, 27, 817, 998, 888, 814
Markedly increased precipitation-lines for §.,, &,,,, and y
64, 958, 1035
Markedly increased precipitation-lines for 8,,, and y
829, 892, 1001
Slightly increased precipitation-lines for 8,, and y
3, 41
Markedly increased precipitation-lines for 6,, and y
897
Slightly decreased precipitation-line for 8,,,
5, 900
Slightly increased precipitation-line for Boy
29, 852
Decrease of 8,, and slight increase of y globulin
precipitation-lines
866
Decrease of 8,, and y globulin precipitation-lines
60, 68, 824
Glucose-6-phosphate Dehydrogenase Activity
and Hemoglobin Types
Dr. Boyer at Johns Hopkins Hospital reported
that all subjects examined had normal glucose-6-
phosphate dehydrogenase activity. On the starch
gel electrophoresis all were of a uniform glucose-6phosphate dehydrogenase electrophoretic type
Class B. This is the type observed in all Americans
of European ancestry and in 70% of Americansof
mixed African and European ancestry.
Electrophoretic studies of hemoglobin showed
that all Marshallese subjects examined had type
AA».
Blood Volume Studies
During the 1961 and 1962 surveys, blood vol-
ume determinations, with use of Cr*?-labeled sodi-
um chromate, were performed on 25 normal
Micronesian and Caucasian persons living in the
Marshall Islands for 1 yr or longer. Table 15
shows the data for 23 of these on red cell mass and
plasma volume based on body weight. From these
data it appears that there was a significant reduction in red cell mass and/or plasma volume in 15
of 23 subjects, both Marshailese and Americans.
During the anticipated 1963 survey, it is planned
to repeat these studies in conjunction with estimations of lean body mass by useof tritiated water.
Evaluation of the above results will be withheld
until completion of the 1963 survey.
immunoelectrophoretic Studies
Immunoelectrophoretic analyses were carried
out on a number of Marshallese sera. These results
are shown in Table 16. Dr. R. Biitler, who carried
out these analyses, reported that “in summary we
have foundneither a paraproteinemia nor a typical
picture of antibody-deficiency-syndrome. The high
frequencyof increases of some of the immunoglob-
ulins is perhaps a typical sign of the investigated
population.”