APPENDIX 6 Pathologic-Anatomical Diagnoses* on 78-yr-old Woman in Exposed Group (No. 56) Main Diagnoses Fracture of vertebral body Li. (No mention is made of the spinal cord.) Fractures of the left 5th to 8th ribs. Retroperitoneal hematoma. Ecchymosesin the vicinity of the rib fractures. Focal fibrosis of the myocardium. Stasis and edema of the jung andliver. Other Diagnoses Patchy endocardial calcification of the heart. Brown atrophy of the myocardium. Generalized arterioclerosis with (a) atheromatosis, in particular of coronary arteries and aorta, (b) Moenckeberg’s media sclerosis, (¢) arteriolar hyalinosis in many organs. Atelectasis of the middle lobe of the right lung. Patchyatelectasis, emphysema, focal fibrosis, and coniosis of the lungs. Pleural adhesions on the right side. Bronchitis, chronic, mucopurulent. Bronchiectasis. Atrophy of bronchial mucosa. (Fat embolism of the lung?) Atrophy,fibrosis, and stasis of the spleen. Atrophy and fibrosis of lymph nodes. (Hemosiderosis of the spleen?) Atrophy of the thymus. Lipomatosis of the bone marrow, particularly in the vertebral body, with decreased mass of blood-formingtissue. Osteoporosis. Scoliosis of the vertebral column. Arteriolosclerotic scars in the kidney (benign nephrosclerosis). Capsular fibrosis of the kidney. Small kidney cysts. Calcifications in the kidney. (Fat embolism of the kidney?) Small papillary cystadenoma of the kidney. Atrophy of the pelvic mucosa of the kidneys. Atrophy andfibrosis of the ovaries. Atrophyand fibrosis of the uterus. Telangiectasis in the uterus. Brown atrophyof the liver. (Hemosiderosis of the liver?) Slight portal fibrosis of the liver. Subserosalfibrosis of the gall bladder. Atrophy andslight fibrosis and lipomatosis of the pancreas. Peritoneal adhesions between hepatic flexure of colon and theliver. Atrophy and nodular hyperplasia of the adrenal glands. Atrophyof the thyroid gland. Small cysts of the thyroid gland. Atrophy of the skin. Atrophy of epidermal appendages of the skin. Greying ofhair. Epidermoid cyst of the skin. Sweat gland cyst of the skin. Nevus pigmentosus of the skin. Elastosis of the skin. Atrophy of the mammary gland. Osteoarthrosis (noted for fingers). Corneal opacities. Arcussenilis, Loss of teeth. *Summary prepared by Dr. Hans Cottier. 74

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