4

lated directly to radiation effects during thefirst
few years post exposure. No prophylactic or specific therapy for radiation effects was ever considered necessary or given. Epidemics of chicken
pox and measles that occurred during the first
year showed nogreater incidenceor severity in the

exposed than in theunexposed Marshalles people.
During thefirst months post exposure about %
of the exposed people exhibited loss ofweight of several pounds. This may possibly have been related
to their radiation exposure, although it wasdiffi-

cult to rule out possible effects due to change of

environment.

At 3 years post exposure the immune response to
primary and secondary tetanus antitoxin was

tested and foundnotto besignificantly different in
the exposed compared with the unexposed populations.
There were 10 deaths in the exposed popula-

tions over the 10-year period (see Table 6). Of

these, 2 deaths were recorded as due to malignan-

cies. The 10 deaths that have occurred in the exposed population represent a mortality rate of 12.2
per 1000 population per annum, compared with
8.3 for the Marshall Islands as a whole (1960).
The somewhat higher deathrate in the exposed
group is partly offset by the higher proportion of
older people; those >65 years of age wereorigi-

nally 20% in the exposed group and only 7% in the
unexposed group.
Growth and development studies on the children
(height, weight, anthropometric measurements,
and radiographic studies for bone age) haverevealed slight retardation in growth and developmentin the boys exposed on Rongelap who were
<12 years of age at the time of exposure, particularly those 12 to 18 months of age at exposure.
Onlyslight immaturity was noted in the female

children of this group. In studies of children born
of exposed parent(s), it was noted that males

showeda slight growth retardation andslightly
lower levels of peripheral blood elements compared with male children of unexposed parents;
however,this latter finding has not been evident
since 1963. Theslight growth difference does not
appearto justify a conclusion that there is an association with exposure of the parent.
It was difficult to evaluate the effects on fertility.

However,a review of the birth rate of the exposed
groupsoverthe past 10 years seemsto indicate no
noticeable effects of their exposure on fertility. The

30 births represent a rate of 61 per 1000 population per annum comparedwith 37.3 for the Marshall Islands (1957). The incidence of miscarriages
andstillbirths in these exposed women was about
twice that in the unexposed women during the
first 4 years after exposure, but no difference has
been noted since then (see Table 8).

A cardwovascularsurvey ofthe adults (1959)" showed
no outstanding differences between the exposed
and unexposed groups. The Marshallese people
appearedto have less hypertension on the whole
than is noted in people in the continental United
States.
An arthritis survey (1959) showed no greatdifferences between the exposed and the unexposed
people, and about the sameincidence asis seen in
American populations.
Ophthalmological surveys showed no remarkable

differences between the exposed and unexposed

groups except possibly a slightly greater number of

cases of pterygia, pingueculae, and corneal scars
in the exposed groups. It is not known whether
these findings are of anysignificance in relation to
their radiation exposure. Slit-lamp observations
showed noopacities of the lens characteristic of
radiation exposure. As a whole, visual and accom-

modation levels in the Marshallese appeared to be
above the average in the U.S. population.
Dental surveys’ showed nosignificant differences
in caries rate between exposed and unexposed

groups. However, the incidence and severity of
peridontal disease wasslightly greater in the exposed group. It is not known whetheror notthis
finding is related to radiation effects. The poor
oral hygiene generally observed in the Marshallese
hadits usual results, namely, high caries rate in
teen-age children, severe peridontal lesions in
adults (heavy calculus andloss of alveolar bone),

and edentulous mouthsin the aged. Radiation exposure did not appearto have affected developing
dentition in the exposed children.
Aging studies were done in which various parameters usually associated with aging were measured
or estimated on a 0 to 4+ scale (skin looseness,

elasticity, and senile changes; graying of the hair

and balding; accommodation, visual acuity, and

arcussenilis; hearing; cardiovascular changesincluding blood pressure and degreesof peripheral
and retinal arteriosclerosis; neuromuscular func-

tion; and hand strength). Comparison of these
measurements in exposed and unexposedindivid-

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