been destroyed. The conditiecn resesbled red atrophy. In the Glissonts shesth wa observed cell infiltration typical of hepatitis. The liver ‘colls which survived had sorewhat, regenerated,although only slightly. We also noted the formation of pservdolabules, Proliferation was comparatively prominent in the biliary ducts, which also revealed bile deposits, Honosiderin deposits appeared in the liver cells and Kupfforts cells. Around the lobules the liver cells wore becoming adipose. The findings indicate that radioactive or other tacle sub~ stances destroyed the livor and that ths destruction was quite corious. Partial roconeraticn had occurroad, but the restored portions wore abcut to be destroyed acvin. These chances corrosrond to the clinical prozress dn wich the sama sysptoma recurred. Put we must vait wmtil the data of Prof. Chamoto and the Kinura Laboratory of Tokyo Univer~ sity will be available tefore wa can reach a conclusion. If it is found that radicactive ole-onts were concentrated azounc tha aroas sf chance, or if any fpertincnt data on sush elexcnts are available, I think we will find then very holpful. A book by an Anerican neared Blooa discusses ocny exporircnts on anicals, using radioactive elecents, There should naturally be great differences between aninals and hurins; but Bloon made radfoautographs of tho liver, having injected radio~ active isotopes into the animils, and demonstrated that the isotopes vere diffused in the liver. Still, I hear that in som coces it does rot bring about v7th chenze in the liver, mo: puolocically cpeeking. I wtarstand he'<.or that a scrious change occurs when plutoniua is vcd. Althsuch riiioretive cle-ants vere found in the liver according %2 the cata of those exmorimants, I think thsre might be cises in which ro ~orpholozical ehinges would eccur and I fcel that this point must be evrcfully watched and studied koreafter. The fect of active meenera~ ticn in the liver, marrow, testicles, and lyuph nodea has greatly helped in analyzing tha findings. The spleon usually becousas edematous when there is degernation in tha liver. But in the case of Mr. there seans tobe no such tendency to cdema’ end on the ccntrary the spleen was small. The blood vessels were considerably enlerged and the lyaphatie follicles were atropiic; but some regeneration was observed. Henatogenic nidi were not demonstrable. , Cholemte repheosis was severe in the Kidneys. Ths tubules contoined evevatnt with conapicuous bile pigment and sidérin deposits were obscrved in the epithelium of the tubules, indicating sons dysfuncticn in tha <stebolisa of fron. I think the liver degeneration fully explains Mr. death, but I think tha heart also hed sozsthing te do with it. Tovard the end, the liver and tha heart, as in tha kidney dogencration, acted somewhat like the two wheels of a cart. The changes sem in the heart were very serious; the myocardium had atrophied, and it night be said that the myocardiag fibsr was turned into connective tissua fiber, In the xnyo-r czrdiua 3:3 observed indi3tInet e:travasation. The hemorrhagic dogenoration below the cyec:.cdiua end the endocardiua was very serious, which substrentintes tha findings of the EXG deserited by Dr, Kunatori. The atrophy cnd inflaccatory chanses of the gastrointestinal mucos2ze are protcbly connected with the nepatic dysfunetion. Since direct influcnee by Bikini ash penetrating the bedy via the mouth 4s still a poszibility, sa shall cencuct very careful invostigations. ~ 13 US DOE ARCHIVES 14