32
Table 16
Immunoelectrophoretic Analyses
Findings
Normal
-
Subject Nos.
15, 30, 20, 78, 8, 76, 92, 77, 9, 14, 33, 16, 2, 21,
57, 47, 4, 37, 10, 73, 12, 914, 835, 838, 875, 844,
865, 896, 982, 836, 832, 936, 955, 956, 957, 830,
960, 939, 893, 979, 840, 833, 915, 967, 975, 882,
898, 1005, 868, 822, 1042, 841, 825, 885
Slightly increased y globulin precipitation-line
53, 71, 86, 52, 63, 22, 32, 87, 59, 54, 79, 6, 66, 1,
45, 928, 856, 883, 940, 1036, 944, 992, 858, 813,
864, 853, 887, 942, 829, 820, 828, 924, 961, 969,
895, 855, 884
Markedly increased y globulin precipitation-line
862, 891
Slightly increased precipitation-lines for 8,,, 4,,,, and ¥
34, 75, 27, 817, 998, 888, 814
Markedly increased precipitation-lines for 4,,, 4,,,, and ¥
64, 958, 1035
Markedly increased precipitation-lines for 8,,, and y
829, 892, 1001
Slightly increased precipitation-lines for 8,, and y
3,41
Markedly increased precipitation-lines for 2,, and y
897
Slightly decreased precipstation-line for 8.,,
5, 900
Slightly increased precipétation-line for Sz,
29, 852
Decrease of 8,, and slight increase of y giobulin
866
Decrease of &,, and y globulin precipitation-lines
60, 68, 824
precipitation-lines
Glucose-6-phosphate Dehydrogenase Activity
and Hemoglobin Types
Dr. Boyer at Johns Hopkins Hospital reported
that all subjects examined had normal glucose-6phosphate dehydrogenase activity. On the starch
gel electrophoresis all were of a uniform glucose-6phosphate dehydrogenase electrophoretic type
Class B. This is the type observed in all Americans
of European ancestry and in 70% of Americans of
mixed African and European ancestry.
Electrophoretic studies of hemoglobin showed
that all Marshallese subjects examined had type
AA.
Blood Volume Studies
During the 1961 and 1962 surveys, blood volume determinations, with use of Cr*'-labeled sodium chromate, were performed on 25 normal
Micronesian and Caucasian persons living in the
Marshall Islands for 1 yr or longer. Table 15
;
shows the data for 23 of these on red cell mass and
plasma volume based on body weight. From these
data it appears that there was a significant reduction in red cell mass and/or plasma volume in 15
of 23 subjects, both Marshallese and Americans.
During the anticipated 1963 survey,it is planned
to repeat these studies in conjunction with estimations of lean body mass by use of tritiated water.
Evaluation of the above results will be withheld
until completion of the 1963 survey.
Immuncoelectrophoretic Studies
Immunoelectrophoretic analyses were carried
out on a number of Marshallese sera. These results
are shown in Table 16. Dr. R. Biitler, who carried
out these analyses, reported that “in summary we
have found neither a paraproteinemia nor a typical
picture of antibody-deficiency-syndrome. The high
frequencyof increases of some of the immunoglob-lins is perhaps a typical sign of the investigated
>pulation.”