72 Hematolog T. KUMATORI order of 350R to 40 and LALANNE, C. M., « logie, 6, 561, (1963) a Jonizing Radiation o Kivicra, K., Tkepa, N., Kimura, K., Kawanisat, H. and Kimuna, M. (1956): ibid. I, 521. Korama, ¥., Kumtaront, T. et al. (1955): Iryo, 9, L. Kusatoart, T. and Miyosxt, K. (1963): Diagnosis and Treatment of Radioactive ietic tissue, Int. At. (1967)). Poisoning, 253, International Atomic Energy Agency, Vienna. We have comparec the curves of Yug cases, and here aga Kuvatoal, T., Isnindana, T., UEDa, T. and Mivosui, K. (1965): Medical Survey of Japanese Exposed to Fallout Radiation in 1954—A Report after 10 Years, National Institute of Radiological Sciences, Chiba. same difference, an Mixamo, ¥., MrrosHt, K., SHimizu, K., IsHixkawa, K., Kuntyama, S., Koyama, ¥. and Kuvtatori, T. (1956): Research in the Effects and Influences of the Nuclear Bomb Test Explosions, II, 1313, Japan Society for the Promotion of Science, Tokyo. Miyvosut, K. and Kumatoat, T. (1935): Acta Haematologica Japonica, 18, 379. Mryvosui, K. and Kumatori, T. (1962): Proceedings of 8th International Congress of Hematology, 1, 29, Pan-Pacific Press, Tokyo. Mirosut, K. and Kumatori, T. (1964): Nihon Ketsuekigaku Zensho, 3, 660, tion of these data * the difference betw- cases and the pw patients was that patients the dose \% with a maximum vé minus 4 per cent, © of accidents the un less, and of the or Maruzen Co., Tokyo. Dr. Kumatoar: I opinion. DISCUSSION Dr. Citeton (U.S.A.): Concerning the one fatality, would you care to comment on the nature of the liver damaue. andits relationship to exter- nal or internal radiation exposure? Dr. KuMatori (Japan) : Since this fatal case was anemic and revealed bone marruw aplasia, he received blood transfusions. Therefore, serum hepatitis can’t be ignored. However, at most cases. In our cases, we used Duke’s method. The bleeding timeis normally 3 minutes, and in 1 or 2 severe cases the bleeding time at the critical stage was as long as about 10 minutes. I think this came back to norma! at about 10 weeks or so after the exposures, though correct data here. [ have no Dr. Sanc: And how about the fib- the same time the existence of radia- rinogen concentration? to decide the cause of his liver damage. ration was almost normal from the beginning of the examination. tion-induced liver damage should be considered. At present it is difficult We should consider the probability of the radiation-induced liver damage, because in some publications we can Dr. Kumatori: Fibrinogen concent- Dr. TusiaNa (France): I would like Kumatori, I would like to ask you to ask Prof. Kumartori if he has an idea of how uniform was the dose delivered to your fishermen. I ask you this question because we have a rather large experience of total-body irradiation for mostly kidney transplants in human patients, and there tell me how long did hemorrhagic The first one is that aplasia of the see a similar histological picture of the liver of a patient who was irradi- ated therapeutically. Dr. Sanc (Korea): I thank you Dr. something about hemorrhagic tendencies on these cases, Would you tendencies continue after the irradiation? Dr. Kumatort: In mycases the he- morrhagic tendencies were not so severe The prolongation of the bleeding time was observed ina fewcases. You can see normal bleeding time in are 2 main differences between your results and the one we have also. blood occurs much earlier in our patients, and the rigidity also occurs much earlier. The 2nd one is that the minimum number of leukocytes is much smaller in our cases, being of the order 1 to 200 leukocytes per cubic millimeter, after a dose of the % 4 i In my ¢