51 HEMATOLOGIC OBSERVATIONS 4.34 Hematological Findings, Group III (Americans) The neutrophile count in general reflected the time course of the total leukocyte count (Fig. 4.5). Neutrophiles accounted almost entirely for the marked rise in total count on postexposure day one, and the values for absolute neutrophile countfluctuated near the control fad [=] = 4] i2 GROUP IIL Leukocyies, 3 and & 10 4 2 8 é 6 34 =z e : i PROJECT 4.1 ° terminations were carried out on these people. In the greater than 5 age groupthe total white bloodcell and neutrophile counts were depressed slightly below control values during the 1st and 2d weeks (Table 4.4). The lymphocyte counts were below control levels consistently, and the total white countequal to the control value obtained on day 29 was due to a neutrophilic leukocytosis. Platelet counts on the 29th day were significantly lower than on the 19th day and, except for the older age males, were lower than control values. The 29th day coincides with the time of maximum depression for the more heavily exposed groups. 6 l2 Ig 24 30 36 POST EXPOSURE DAY 42 48 Ficure 4.5—Serial total leukocyte, neutrophile and lymphocyte count in cxzposed Americans (Group ITI). values thereafter in the course of the study. The lymphocyte counts fell to below control levels in the first few days, and remained at a level approximately 75 percent of the control value throughout most of the remainder of the observation period. In Groups I and IT the fluctuations in the total leukocyte count were accounted for almost Table 4.5.—Group IIJ Americans Mean Blood Count by Day “oct” NEUTRO- Tlie Lee 8 2 ee ee 9 Loe ee 10. 0 eee | 12___- eee 13___------ ee ee ee ee 16.02 eee 16_. 2-02 -eeee 19_. ee 23-2 - eee 2 a 39_ 0-2 ee ~enuee 43 002 2- ~e eee eee nee _47.000 ee aoe B1_ Lee 9. 6 6. 6 6. 2 6.3 6. 2 6. 0 6. 1 6. 1 8.1 7.9 6. 7 7.2 6. 7 6. 8 7.6 7.8 5. 7 6.1 4.3 4.0 3. 8 3. 9 3. 7 3. 7 3. 8 4.7 4.8 4,2 4.1 4,1 3.8 4, 4 4.6 3. 2 330 Leelee 21 Lule 20 | LLL 22 _Lu__. ys a 21) La ee 21 elle 20 _uuLLe 2.9 22. 0 2.7 22. 2 2.1 17.9 2,5 14, 4 2,2 16.1 2.7 20. 1 2.9 21.8 3.1 20. 2 2,2 18. 8 0. 1 19 2. 0 2. 2 1.8 1.5 17 1.7 2.8 2. 4 1.6 2. 0 1.8 1. 4 1.4 2.7 2. 4 1.6 0.5 0. 4 0.3 0. 5 0.7 12 1.3 2.5 2. 1 14 2. 1 2,2 1.5 2.0 1.5 17 Kwaj-American Controls __._! 7.8 4.1 3. 1 2. 6 2.7 PB. Day mugs 60 LYMPHO- gemas . Eosixo0- Srtag™ |ton| ress 23. 8