51

HEMATOLOGIC OBSERVATIONS

4.34

Hematological Findings, Group III
(Americans)

The neutrophile count in general reflected the
time course of the total leukocyte count (Fig.
4.5). Neutrophiles accounted almost entirely
for the marked rise in total count on postexposure day one, and the values for absolute
neutrophile countfluctuated near the control

fad

[=]
=

4] i2

GROUP IIL

Leukocyies,

3

and

& 10
4
2 8
é

6

34

=z

e
:

i

PROJECT 4.1
°

terminations were carried out on these people.
In the greater than 5 age groupthe total white
bloodcell and neutrophile counts were depressed
slightly below control values during the 1st and
2d weeks (Table 4.4). The lymphocyte counts
were below control levels consistently, and the
total white countequal to the control value obtained on day 29 was due to a neutrophilic
leukocytosis.
Platelet counts on the 29th day were significantly lower than on the 19th day and, except
for the older age males, were lower than control
values. The 29th day coincides with the time
of maximum depression for the more heavily
exposed groups.

6

l2

Ig

24
30
36
POST EXPOSURE DAY

42

48

Ficure 4.5—Serial total leukocyte, neutrophile and
lymphocyte count in cxzposed Americans (Group ITI).

values thereafter in the course of the study.
The lymphocyte counts fell to below control
levels in the first few days, and remained at a
level approximately 75 percent of the control
value throughout most of the remainder of the
observation period.
In Groups I and IT the fluctuations in the
total leukocyte count were accounted for almost

Table 4.5.—Group IIJ Americans Mean Blood Count by Day

“oct”

NEUTRO-

Tlie Lee
8 2 ee ee
9 Loe ee
10. 0 eee
|
12___- eee
13___------ ee ee ee ee
16.02 eee
16_. 2-02 -eeee
19_. ee
23-2 - eee
2
a
39_ 0-2 ee ~enuee
43 002 2- ~e eee eee nee _47.000 ee aoe
B1_ Lee

9. 6
6. 6
6. 2
6.3
6. 2
6. 0
6. 1
6. 1
8.1
7.9
6. 7
7.2
6. 7
6. 8
7.6
7.8
5. 7

6.1
4.3
4.0
3. 8
3. 9
3. 7
3. 7
3. 8
4.7
4.8
4,2
4.1
4,1
3.8
4, 4
4.6
3. 2

330
Leelee
21
Lule
20
| LLL
22
_Lu__.
ys a
21)
La ee
21
elle
20
_uuLLe
2.9
22. 0
2.7
22. 2
2.1
17.9
2,5
14, 4
2,2
16.1
2.7
20. 1
2.9
21.8
3.1
20. 2
2,2
18. 8

0. 1
19
2. 0
2. 2
1.8
1.5
17
1.7
2.8
2. 4
1.6
2. 0
1.8
1. 4
1.4
2.7
2. 4

1.6
0.5
0. 4
0.3
0. 5
0.7
12
1.3
2.5
2. 1
14
2. 1
2,2
1.5
2.0
1.5
17

Kwaj-American Controls __._!

7.8

4.1

3. 1

2. 6

2.7

PB. Day

mugs

60

LYMPHO-

gemas

.

Eosixo0-

Srtag™ |ton| ress

23. 8

Select target paragraph3