5.

Areas of Difference between the Methods

ICRP uses 12m2 as the surface area for endosteal tissue.
equally divided between trabecular

This is

and cortical bone and the absorbed fraction

is assumed to be the same in each, (ICRP 30, Part 1.)

I have not

Spiers uses 16m2 for the surface area of endosteal tissue.
been able to determine what the distribution
cortical bone (ref. 2 and 3).

is between trabecular

The dose factor for trabecular

and

endosteal cells

is 3.11 while that for cortical endosteal cells is 50% higher at 4.7.
could reflect a difference
trabecular

in the distribution

and cortical bone.

This

of the endosteal mass between

Spiers was the absorbed fraction for Pu rather

than an average value for alpha emitters as used by ICRP and this would make
some difference.

Spiers does make the point that cortical endosteal tissue

may not be at as high a risk per unit dose as the trabecular endosteal tissue.

I think that the dose rates Spiers lists in reference

1 of 129 rad/UCi-y

for trabecular endosteal cells and 193 rad/~Ci-y for cortical endosteal
cells (compared with 16.9 rad/~Ci-y for bone marrow) are wrong.

Based on

these numbers, the trabecular endosteal cell ratio to bone marrow is 7.6 while
that for cortical endosteal cells is 11.4.

This is inconsistent with his

published dose factor ratios of 0.26 for marrow, 3.11 for trabecular surface
cells and 4.7 for cortical surface cells which give ratios of surface cells to
marrow of 12 and 18 respectively.
However, as I mentioned before, we use a dose conversion

of 338 rem/uCi-y

to develop the bone marrow dose and multiply by a factor of 12 to get the
surface cell dose.

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