C.W. Mays - Page 10 Table 4 BSTIMATED THYROID CANCERS FOR THE 565 INFANTS NLAR ST. GEORGE IN 1953 ASSUMPTION NUMBER OF CANCERS (A) Iodine 131 effect equals X-ray effect (B) Effect equals 1/10 of X-ray effect 2 - 9 0.2 - O49 (C) High Threshold wm 0 eee "NATURAL" INCIDENCE BY 15 YEARS OF AGE 0.0L If the additional doses received before birth and in later childhood had been included, the estimated number of radiation~induced cancers would have been even higher than shown in Tables 3 and 4. DISCUSSION 1) The St. George study has the advantage that the "natural" occurrence of childhood thyroid cancers is extremely unlikely among the 565 infants exposed in 1953. The probability of one natural case is one in one hundred whereas the chance for two natural cases is only one in ten thousand. Is it possible that genetic or environmental factors might increase the "natural" incidence in this region one hundred thousand by a factor of / to ten / times greater than for the rest of the USA? I do not know. test this hypothesis. But I do know how to Individual estimates should be Iade of the most probable dose to each St. based on source of milk and thyroid size. George child These children should then be classified into graded dose categories. The high-dose children will probably be those who drank local milk as infants fror 19 May - 19 June 195% (and to a lesser extent, from 17 March - 17 April 1953, and from 31 August - 30 September 1957). * The approximate size of a child's thyroid at iodine 131 intake can be calculated from his age at intake. DOEARCHIVES 4b

Select target paragraph3