i

wee

ae!

ee Nk me

many soldiers had nausea and vomiting, recovered,

eae

te eS Fe Fame

3

we cepa pH

te Le

Aa wet pactimneeaAYE aes

felt well, returned to

duty to later develop purpura, epilation, oral cutaneous lesions, and then
cied of infection.

This is well-docuriented by Gughtersen and Warren (1).

Despite

conditions

the

chaotic

that existed

Kikuchi and Yakisaka (19) indicates
granulocytes in individuals

that

in Hiroshima,

there was more

that could be assfguned

to

the

data

of

rapid decrease of

the Survival

Improbable and Survival Possible as compared to the Survival Probable
group.
Survival Probable:
not have had

This group consists of individuals who may or may

transient nausea and vomiting on the day of exposure,

In this

group, characterized by the Marshallese (6), there is no further evidence
of effects of exposure except the hematologic changes that can be detected
by serial studies of the blood with particular reference
lymphocytes and platelets.
within 4€ hours, and show

exposure.

to granulocytes,

The lymphocytes may reach low levels early,
little evidence of recovery for many months after

The granulucytes may show some depression during the second and

third week.

However, considerable variation is encountered.

_in the granulocytes during

A late fall

the 6th or 7th week after exposure may occur.

. Platelet counts reach the lowest levels at approxmately the 30th day at the
time when maxinum bleeding was observed in the Japanese who were exposed at

i, Hiroshima and Nagasaki.
" Marshallese exposed

The lowest platelet counts were also seen in the

to fallout radiation around 30 days after exposure.

In

B this group individuals with neutrophil counts below 1000/1 may be
completely asymptomatic.

Likewise, ihdividuals with platelet counts of

75,000/u1 ox less may show no external signs of bleeding.
defenses against infection are
individuals with

lowered by

Lven though the

this sublethal dose of radiation,

these severe degrees of hematologic depression may not

It is generally believed that premature administration

Effects of a Single Dose of Gamma Radiation
Analysis of a Possible Human LDc,
>

In the first place, in all reality,

,

the mortality response of tan

on Tadiation is not known with any degree of precision.
.the LDsg in

the classic pharmacologic sense;

that

is,

One should think
the mortality

Select target paragraph3