anemia from suppression of red cell production and hemorrhage. descriptions of Detailed this syndrome in man and animals are described (1,2,5-13). This picture of the three radiation syndromes, which overlap to a certain extent, is based primarily upon animal experimentation. Human experienee (1,2,14-20) indicates that man corresponds reasonably closely to the general mammalian response. There are some differences the time of occurrence of signs and symptoms. in respect to The experience of the Japanese at Hiroshima and Nagasaki exposed to gamma’ radiation from a high-altitude nuclear device in which the fireball did not touch the ground are described in detail by Oughtersen and Warren (1). Hubner and Fry (2) have gathered together the total human experience in radiation injury and “tts Management, with the exception of and the Japanese atomic bomb casualties the Marshallese fallout casualties. _(1,15,24), nor would one have expected it to be observed since doses to the syndrome were well within total destruction and no The GIS, with deaths in the first week, are well documented clinically and pathologically as are deaths from the HS (1,15,18). "case of man, the sequential sequence of deaths and depression of blood “counts is different from that in animals. develop ia man. It takes longer for the HS to For example, deaths from infection were most prevalent in Ypanese as late as mals, In the oe P survival. the area of Sa ‘produce nerrergenpernememes o> The CNS was not observed by the Japanese at Hiroshima or Nagasaki eens Radiation Injury in the Japanese at Hiroshima and Nagasaki: the seventh week. This is in contrast to other where deaths from the acute phase are uncommon later fy). than the The correlation of neutrophil c unts with tality, is shown in Figure 2. The data in Figure 2 are based on dogs rare illustrated in Figures 3 and 4. eat leukocyte counts in In addition, it was shown that the Japanese were observed in week after exposures to the nuclear radiation (20). the fifth to the A comparable ence in the depression of granulocytes was also seen in the Marshallese 4 é ed to fallout radiation (5). ee omnes oe Po SeARERa TETR Meee s Sebheen