RMI Nuclear Justice Documents

35

TSH concentrations were normal. For this reason,
TBG-binding capacities were determined in a
numberof subjects with abnormal Ty, values.
' TBG analyses were done on sera from 56 sub-

jects (25 Rongelap and 31 Utirik) selected as representative of three groups: people with low, normal, or high plasma T4 concentrations. Two

methods were used: TBG was measured by radioimmunoassay (M.C. Gershengorn and J. Robbins.
unpublished observations, 1974) and TBG-binding capacity bv reverse-flow paper electrophoresis.
The results were comparable since the mean ratio
of TBG-binding capacity (ug Ty/dl) to TBG
(mg/dl) was 13,9. On the basis of one mole T4

Table 31

Total and Free Thyroxine, Thyroxine-Binding Globulin, and Thyrotropin Levels in Marshallese

Subject No.

TBG,yg/dl

Ta, pe/dl

Subjects with TBG-bindcapacity <14 pg T./dl
827
7.6 (1.06) *
5.1
917
7.0 (1.20)
4.4
981
8.0 (0.69)
4.4
2115
7.7
4.4
2126
9.1
4.9
44
7.0
4.0
174
7.1
4.1
2193
11.1 (1.03)
4.8
2290
13.7
3.2
2248
11.9 (0.94)
3.8
2185
4.6
Mean
9,02
4,34
§.D.
2.39
+0.543

Subjects with TBG-bindingcapacity 14 to 26 ug Ts/di
850
2135
2137
2212
2206
2182
2218
2221
2232
2257
2168
2136
2230

14.0 (1.04)
15.5
19.9 (1.37)
20.1
17.7
14.4
14.3
15.6
16.2 (1.54)
17.3
14.1
15.5 (1.06)
21.9 (1.28)

Mean

S.D.

4.6
6.1
9.2
5.0
7.4
5.0
3.0
4.8
4.8
8.8
4.2
7.7
6.1

Mean
$.D.

TSH, pU/mi

3.37
3.53
3.24
3.21
3.20
3.76
4,23
3.23
3.12
2.94
2.80
3.33
+0.40

1.72
1.35
1.43
Lal
1.37
1.50
1.73
1.55
0.998
1,12
1.29
144
0.230

~
3.1
2.3
<1.0
<3.0
52.5
<1.0
4.2
3.6
<2.5

3.08
2.94
2.90
1.84
2.97
2.92
3.04
2.68
2.42
2.94
2.72
215
1.45

1.42
1.79
2.67
0.92
2.05
1.46
0.912
1,29
1.16
2°57
1.14
1.66
0.885

16.63

5.9

2.60

1.87

+0.503

37.0 (1.52)
35.7
56.1 (4.56)
47.6 (3.92)
32.8
51.8
43.5
+9.62

*TBG by RIA, mg/ml.

OGs'o2

Free T,, ng/dl

2.58

Subjects with TBG-binding capacity >26 ue T,/dl

2138
2229
aol
911
2217
2256

DFT, x 10¢#

9.0
5.9
12.9
13.6
7.0
18.2
11.05
4.63

2.01
1.53
1.22
0.872
1.88
0.991
1.42
0.468

,

2.6
21
2.6
<25
2.8
2.5
3.6
<5.0
6.0
2.0
2.5
2.1
4.9

1353

+0.597
L.81
0.903
1.54
1.19
1.32
1.80
1.43
*+0.358

24
10.8
2.1
2.7
44