32
with marked growth retardation (Nos. 3 and 5).
Ty, levels before surgerv were lowerin subjects exposed in childhood than in unexposed controls.
Subjects exposed as adults who developed either
benign or malignant thyroid lesions did not show
notable impairment of thyroid function. The
serum iodine levels of exposed and unexposed
people for the past 15 years are given in Appendix 8.
In 1965, the rates of urine and thyroid accumu-
lation of 132] were measured over a 4-hr period in
21 Rongelap subjects, of whom 9 were unexposed
and 12 were exposed as adults.18 The data are
summarized in Table 26. Compared with North
American normal values obtained in 196318
(urine, Agi 2=2; thyroid, 421221; thyroid fraction
20.33), both the exposed and unexposed Mar-
shallese showed slow urine and thyroid transfer
rates of extrathyroid iodide but a high thyroid fraction. Similar studies done in*1972 on 12 Rongelapese without detectable thyroid abnormalities,
Table 28
Thyroid Status of Exposed Rongelap Subjects Without Recognized Thyroid Lesions, {974
Plasma T,, pe/dl
Subject No.
and sex
Age
(1974)
Pre-TSH
24 hr post-TSH
Increment*
+M
6M
7M
38
21
36
6.9
6.8
4,7
7.8
8.3
3.3
0.9
1.5
0.6
10M
44
9.2
12.8
3.6
<1.0
5.3
4.4
6.3
3.1
2.6
5.1
4.4
3.2
39
3.1
9M
+2
\2F
38
4.5
6.5
3.3
8.7
2.2
16M
24F
34F
35 M
37M
39 F
41M
48 F
51 F
66 F
59
33
65
33
40
35
64
26
45
52
6.4
8.2
7.1
5.9
4.6
8.3
6.0
7.2
6.9
7.0
8.3
12.1
10.6
7.8
6.6
11.5
9.4
12.2
9.1
9.4
L.9
3.9
3.5
1.9
2.0
3.2
3.4
5.0
2.2
2,4
70 F
35
79
11.8
3.9
7.0
7.1
9.1
7.8
6.7
8.6
11.4
1.6
0.8
1.0
2.0
0.9
2.4
3.6
68 M
64
73M’
38
8.9
7.8
76 M
78 EF
80 M
81F
82 M
83 M
85 M
31
57
66
28
70
20
20
3.4
6.3
8.1
3.8
3.8
6.2
7.8
11M
70
6.8
iF
14F
22F
27M
44M
58 F
63 F
67 F
71F
32M
47M
74
45
37
36
24
79
56
34
48
24
28
Mean + S.D.
3.1
10.4
12.0
1.6
4,2
4.5
+.4
18.5
9.1°
-
14.4
16.7
21.7
18.4
6.0
1.5
2.3
4.7
8.8
3.0
3.4
3.8
7.0
2.3
18.6
25.5
21.2
ae:
3.0
35
75
5.8
8.2
82
7.4
42
75
8.4
6.622 1.7
7.0
3.9
2.1
TBGbinding capacity,
ug Ty/dl
3.9
6.7
*Normal in 13 Pittsburgh subjects: 4.71.0 ue/dl.%
TK:
0.8
Plasma TSH.**
pU/ml
2.7
2.7
4.2
5.3
6.3
2.7
103
<1.0
7.0
2.3512
**Measured in pre-TSH samples. Normalis <5 U/ml.